Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 9/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499008 | 0.76 | PPARG (0.48) | PPARGMAPTPPARAPPARDNPC1 | |
| SCHEMBL12493300 | 0.75 | TAS1R3 (0.60) | TAS1R3TAS1R1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4339988 | 0.74 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL23226754 | 0.73 | FFAR4 (0.59) | MAPTNPC1RAB9ASMN1; SMN2FFAR4 | |
| SCHEMBL4328026 | 0.73 | CYP2D6 (0.47) | PPARGPPARAPPARD | |
| SCHEMBL4347157 | 0.73 | PPARA (0.61) | PPARGPPARAPPARD | |
| SCHEMBL13440181 | 0.72 | FFAR4 (0.58) | MAPTNPC1RAB9ASMN1; SMN2FFAR4 | |
| SCHEMBL4336608 | 0.72 | PPARG (0.42) | PPARGMAPTPPARAPPARDNPC1 | |
| SCHEMBL4327205 | 0.71 | ATM (0.42) | PPARGMAPTPPARAPPARDRAB9A | |
| SCHEMBL4474939 | 0.70 | PPARG (0.44) | PPARGMAPTPPARAPPARDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |