Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328033 | 0.83 | FFAR1 (0.41) | FFAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4347161 | 0.79 | FFAR1 (0.53) | FFAR1ALDH1A1SMN1; SMN2PPARGAKR1C3 | |
| SCHEMBL19122117 | 0.75 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2LMNAKMT2AL3MBTL1 | |
| SCHEMBL4339988 | 0.73 | PPARG (0.44) | FFAR1KMT2APPARG | |
| SCHEMBL24313765 | 0.72 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL1508434 | 0.72 | FFAR1 (0.42) | FFAR1PPARG | |
| SCHEMBL29469835 | 0.72 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL25160041 | 0.71 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4948306 | 0.69 | TSHR (0.66) | SMN1; SMN2LMNAKMT2AL3MBTL1 | |
| SCHEMBL23000616 | 0.68 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |