SCHEMBL4340087

SCHEMBL4340087

CC1(C)c2ccccc2-c2ccc(-c3ccc(-c4nc5ccccc5nc4-c4ccc(-c5ccc6c(c5)C(C)(C)c5ccccc5-6)cc4)cc3)cc21

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 5/20 0.41
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 5/20 0.41
GAA P10253 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PDK2 Q15119 5/20 0.40
KMT2A Q03164 2/20 0.40
THRB P10828 1/20 0.40
MEN1 O00255 1/20 0.40
AKT1 P31749 1/20 0.39
AKT2 P31751 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21667422 0.94 TDP1 (0.49) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL15041040 0.94 TDP1 (0.42) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL13614924 0.93 KDM4E (0.47) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL21667598 0.92 LMNA (0.39) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL13726419 0.90 MAPK14 (0.49) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL12690524 0.90 TDP1 (0.39) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL18996717 0.89 TDP1 (0.44) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL14508285 0.88 TDP1 (0.49) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL14508274 0.88 TDP1 (0.49) TDP1L3MBTL1KDM4EALDH1A1LMNA
SCHEMBL13727997 0.88 MAPK14 (0.53) TDP1L3MBTL1KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130285035-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-10-31 US disclosed
US-20130285035-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-10-31 US disclosed
US-20120193619-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND LIGHTING DEVICE USING SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-02 US disclosed
US-20120193619-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND LIGHTING DEVICE USING SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-02 US disclosed
US-7612204-B2 Quinoxaline derivative, and light-emitting element and light-emitting device using quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-11-03 US disclosed
US-7612204-B2 Quinoxaline derivative, and light-emitting element and light-emitting device using quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-11-03 US disclosed
US-7612204-B2 Quinoxaline derivative, and light-emitting element and light-emitting device using quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-11-03 US disclosed
EP-2084138-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING QUINOXALINE DERIVATIVE Semiconductor Energy Laboratory Co, Ltd. (JP) 2009-08-05 EP disclosed
WO-2008047589-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-24 WO disclosed
WO-2008047589-A1 QUINOXALINE DERIVATIVE, AND LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE USING QUINOXALINE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-24 WO disclosed
US-20080091012-A1 Quinoxaline Derivative, And Light-Emitting Element And Light-Emitting Device Using Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-17 US disclosed
US-20080091012-A1 Quinoxaline Derivative, And Light-Emitting Element And Light-Emitting Device Using Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-17 US disclosed
US-20080091012-A1 Quinoxaline Derivative, And Light-Emitting Element And Light-Emitting Device Using Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091012-A1 Quinoxaline Derivative, And Light-Emitting Element And Light-Emitting Device Using Quinoxaline Derivative NQO1, GLB1, PDXK TDP1 2057/4885L3MBTL1 1370/4885KDM4E 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.