SCHEMBL434114

SCHEMBL434114

CCCCCc1cc(N)ccc1-c1ccc(N)cc1CCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 6/20 0.44
HTR2A P28223 1/20 0.42
GPR84 Q9NQS5 1/20 0.42
SRC P12931 1/20 0.42
TSHR P16473 2/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX5 P09917 1/20 0.42
MAPT P10636 1/20 0.42
TYR P14679 1/20 0.42
ALOX15 P16050 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GPR3 P46089 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
PRKCI P41743 1/20 0.39
ACHE P22303 1/20 0.38
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12798389 0.98 HTR2A (0.46) TLR8HTR2AGPR84SRCTSHR
SCHEMBL5381974 0.94 TLR8 (0.42) TLR8HTR2AGPR84SRCTSHR
SCHEMBL15478264 0.90 LIPG (0.47) TLR8HTR2AGPR84SRCTSHR
SCHEMBL360104 0.89 CNR1 (0.47) TLR8HTR2AGPR84SRCTSHR
SCHEMBL11117159 0.88 CNR1 (0.49) TLR8HTR2AGPR84SRCTSHR
SCHEMBL28596302 0.88 CNR1 (0.49) TLR8HTR2AGPR84SRCTSHR
SCHEMBL10347952 0.86 CNR1 (0.48) TLR8HTR2AGPR84SRCTSHR
SCHEMBL6835567 0.86 TYR (0.47) TLR8HTR2AGPR84SRCTSHR
SCHEMBL5824329 0.85 PRKCI (0.42) TLR8TSHRMEN1TP53CYP3A4
SCHEMBL5379403 0.84 TYR (0.46) TLR8HTR2AGPR84SRCTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8253568-A None JP disclosed
US-8102113-B2 Quinoxaline-containing compounds and polymers thereof FUJI XEROX CO., LTD. (JP) 2012-01-24 US disclosed
US-7910748-B2 Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2011-03-22 US disclosed
US-7902382-B2 Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2011-03-08 US disclosed
US-7763737-B2 Carbazole compound, and polymer thereof FUJI XEROX CO., LTD. (JP) 2010-07-27 US disclosed
US-20100133995-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-06-03 US disclosed
US-20100137553-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-06-03 US disclosed
US-7659410-B2 Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-02-09 US disclosed
US-7589166-B2 Thiophene-containing compound and polymer thereof FUJI XEROX CO., LTD. (JP) 2009-09-15 US disclosed
US-20080312453-A1 Novel Carbazole Compound, and Polymer Thereof FUJI XEROX CO., LTD. (JP) 2008-12-18 US disclosed
US-5734003-A INTERMOLECULAR CONDENSATION OF CHARGE TRANSPORTING COMPOUND HAVING HYDROXYL GROUPS; EXCELLENT SOLUBILITY, FILM FORMING, STRENGTH AND STABILITY TO REPEATED USE FUJI XEROX CO., LTD. (JP) 1998-03-31 US disclosed
US-5731118-A Charge transporting random copolyester resin, process for producing the same and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1998-03-24 US disclosed
US-5654119-A ELECTROPHOTOGRAPHIC PHOTORECEPTORS FUJI XEROX CO., LTD. (JP) 1997-08-05 US disclosed
US-5639581-A ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI XEROX CO., LTD. (JP) 1997-06-17 US disclosed
US-5604064-A USEFUL IN ELECTROPHOTOGRAPHIC PHOTORECEPTORS FUJI XEROX CO., LTD. (JP) 1997-02-18 US disclosed
JP-H08253568-A NEW CHARGE TRANSPORT POLYMER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME FUJI XEROX CO LTD 1996-10-01 JP disclosed
EP-0713149-A1 Organic electronic device using charge transporting copolyester FUJI XEROX CO., LTD. (JP) 1996-05-22 EP disclosed
EP-0710893-A1 Charge transporting polymer, process for producing the same, and organic electronic device containing the same FUJI XEROX CO., LTD. (JP) 1996-05-08 EP disclosed
EP-0687958-A1 Charge-transporting polymer and organic electron device using same FUJI XEROX CO., LTD. (JP) 1995-12-20 EP disclosed
EP-0686879-A1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1995-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312453-A1 Novel Carbazole Compound, and Polymer Thereof ARL1, CDKL1, PARP11 TLR8 4156/4885HTR2A 2152/4885GPR84 1255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.