SCHEMBL4343203

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4332627	0.91	MAPK8 (0.49)	WNT1DYRK1AMAPK8MAPK10MAPK14
	SCHEMBL4334482	0.88	MAP4K4 (0.51)	DYRK1AMAPK8MAPK1MAP2K4CDK4
	SCHEMBL4340999	0.83	WNT1 (0.51)	WNT1DYRK1AMAPK8MAPK10MAPK14
	SCHEMBL2861793	0.79	DYRK1A (0.53)	WNT1DYRK1AMAPK8MAP2K4
	SCHEMBL4334601	0.79	MAP4K4 (0.50)	DYRK1AMAPK8MAPK1MAP2K4CDK4
	SCHEMBL27558524	0.79	MAP2K4 (0.54)	DYRK1AMAPK1MAP2K4CSNK1DNTRK1
	SCHEMBL4332113	0.78	KDM4E (0.52)	WNT1DYRK1AMAPK1ALDH1A1SMN1; SMN2
	SCHEMBL4328143	0.78	HPGD (0.53)	MAPK8MAPK1ALDH1A1SMN1; SMN2
	SCHEMBL2862186	0.78	SMN1; SMN2 (0.56)	DYRK1AMAPK8MAPK1SMN1; SMN2CSNK1D
	SCHEMBL2857674	0.78	MAP2K4 (0.60)	MAPK1MAP2K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.