Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 20/20 | 0.56 |
| ▸ | LOX | P28300 | 14/20 | 0.56 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL13570541 | 0.98 | LOXL2 (0.54) | LOXL2LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL30931587 | 0.98 | LOXL2 (0.54) | LOXL2LOXLOXL3 | |
| SCHEMBL30398543 | 0.83 | LOXL2 (0.59) | LOXL2LOXLOXL3 | |
| SCHEMBL4550458 | 0.83 | LOXL2 (0.59) | LOXL2LOXLOXL3 | |
| SCHEMBL30931700 | 0.83 | LOXL2 (0.62) | LOXL2LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL4770707 | 0.82 | LOXL2 (0.60) | LOXL2LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL22287295 | 0.82 | LOXL2 (0.60) | LOXL2LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL4770701 | 0.82 | LOXL2 (0.57) | LOXL2LOXLOXL3 | |
| SCHEMBL4930812 | 0.80 | LOXL2 (0.59) | LOXL2LOXLOXL3 | |
| SCHEMBL25302623 | 0.78 | LOXL2 (0.61) | LOXL2LOXLOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630404-A1 | UREA COMPOUNDS AS ACTIVATORS OF POTASSIUM CHANNELS KV7.2/7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS | ANGELINI PHARMA S.P.A. (IT) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121048-A1 | UREA COMPOUNDS AS ACTIVATORS OF POTASSIUM CHANNELS KV7.2/7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS | ANGELINI PHARMA S.P.A. (IT) | 2024-06-13 | — | — | WO | disclosed |
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | disclosed |
| EP-2520566-A1 | New Pharmaceutical Compounds | Orion Corporation (FI) | 2012-11-07 | — | — | EP | disclosed |
| WO-2009145720-A1 | ISOINDOLINE DERIVATIVES COMPRISING ADDITIONAL HETEROCYCLIC GROUPS AND THEIR USE IN THE TREATMENT OF PAIN DISORDERS | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | WO | disclosed |