SCHEMBL4344019

SCHEMBL4344019

O=C(O)C1C(C(=O)O)C(C(=O)OC(=O)C2C(C(=O)O)C(C(=O)O)C2C(=O)O)C1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.35
TDP1 Q9NUW8 3/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
TSHR P16473 2/20 0.33
PPM1B O75688 2/20 0.33
PTPN1 P18031 2/20 0.33
PPP1CC P36873 2/20 0.33
APEX1 P27695 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
PMP22 Q01453 1/20 0.33
TFPI2 P48307 1/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
ALDH1A1 P00352 2/20 0.32
GRM2 Q14416 1/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15400430 1.00 POLB (0.35) POLBTDP1CTDSP1TSHRPPM1B
SCHEMBL11262302 0.89 POLB (0.40) POLBTDP1CTDSP1PPM1BPTPN1
SCHEMBL1963633 0.78 POLB (0.47) POLBTDP1CTDSP1TSHRAPEX1
SCHEMBL676573 0.78 POLB (0.47) POLBTDP1CTDSP1TSHRAPEX1
SCHEMBL9782996 0.78 POLB (0.47) POLBTDP1CTDSP1TSHRAPEX1
SCHEMBL9782987 0.78 POLB (0.47) POLBTDP1CTDSP1TSHRAPEX1
SCHEMBL9271352 0.78 POLB (0.47) POLBTDP1CTDSP1TSHRAPEX1
SCHEMBL9782992 0.78 POLB (0.47) POLBTDP1CTDSP1TSHRAPEX1
SCHEMBL9782989 0.78 POLB (0.47) POLBTDP1CTDSP1TSHRAPEX1
SCHEMBL9782982 0.78 POLB (0.47) POLBTDP1CTDSP1TSHRAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024095927-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED RELIEF PATTERN USING SAME, AND METHOD FOR PRODUCING POLYIMIDE FILM USING SAME 旭化成株式会社 2024-05-10 WO disclosed
WO-2024090567-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PRODUCTION METHOD FOR POLYIMIDE CURED FILM USING SAME, AND POLYIMIDE CURED FILM 旭化成株式会社 2024-05-02 WO disclosed
CN-116693927-A Porous polyimide composition and polyamic acid composition 旭化成株式会社 2023-09-05 CN disclosed
CN-115745831-A Indenyl-containing diamine and preparation method and application thereof, polyimide film and application thereof 东华大学 2023-03-07 CN disclosed
WO-2023286686-A1 MULTILAYER BODY OF INORGANIC SUBSTRATE AND TRANSPARENT HEAT-RESISTANT POLYMER FILM 東洋紡株式会社 2023-01-19 WO disclosed
WO-2023286685-A1 LAMINATE OF INORGANIC SUBSTRATE AND HEAT-RESISTANT POLYMER FILM 東洋紡株式会社 2023-01-19 WO disclosed
US-11505729-B2 Materials for use as adhesive and for surface sealing EPG (ENGINEERED NANOPRODUCTS GERMANY) AG (DE) 2022-11-22 US disclosed
WO-2022186002-A1 LAMINATE OF INORGANIC SUBSTRATE/POLYMER FILM LAYER WITH ATTACHED PROTECTIVE FILM, LAMINATE STACK, LAMINATE STORAGE METHOD, AND LAMINATE TRANSPORT METHOD 東洋紡株式会社 2022-09-09 WO disclosed
US-20210277185-A1 COMPOSITION AND USE THEREOF JSR CORPORATION (JP) 2021-09-09 US disclosed
US-20190023955-A1 MATERIALS FOR USE AS ADHESIVE AND FOR SURFACE SEALING EPG (ENGINEERED NANOPRODUCTS GERMANY) AG (DE) 2019-01-24 US disclosed
US-20090058269-A1 Charge-transporting varnishes containing charge-transporting polymers and organic electroluminescent devices made by using the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-05 US disclosed
EP-1905804-A1 CHARGE-TRANSPORTING VARNISHES CONTAINING CHARGE-TRANSPORTING POLYMERS AND ORGANIC ELECTROLUMINESCENT DEVICES MADE BY USING THE SAME Nissan Chemical Industries, Ltd. (JP) 2008-04-02 EP disclosed
EP-0821665-B1 CYCLOBUTANE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHASE AND PROTEIN FARNESYLTRANSFERASE ABBOTT LAB (US) 2001-10-04 EP disclosed
EP-1090908-A2 Cyclobutane derivatives as inhibitors of protein farnesyltransferase ABBOTT LABORATORIES (US) 2001-04-11 EP disclosed
EP-0677039-B1 CYCLOBUTANE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE ABBOTT LAB (US) 1999-03-10 EP disclosed
US-5831115-A CYCLOBUTANECARBOXAMIDES ABBOTT LABORATORIES (US) 1998-11-03 US disclosed
US-5783593-A FUNGICIDE; ANTICHOLESTEROL AGENT ABBOTT LABORATORIES (US) 1998-07-21 US disclosed
US-5631401-A Inhibitors of protein farnesyltransferase and squalene synthase ABBOTT LABORATORIES (US) 1997-05-20 US disclosed
WO-1996034850-A1 CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE ABBOTT LABORATORIES (US) 1996-11-07 WO disclosed
US-5124825-A Liquid crystal display device KONICA CORPORATION (JP) 1992-06-23 US disclosed