Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66048 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782982 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL338159 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9271352 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782992 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782989 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL676573 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782996 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL9782987 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA | |
| SCHEMBL911207 | 1.00 | POLB (0.47) | POLBTDP1CTDSP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152347-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORP (US) | 2017-06-01 | — | — | US | disclosed |
| US-20150321996-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION | 2015-11-12 | — | — | US | disclosed |
| US-9066972-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2015-06-30 | — | — | US | disclosed |
| US-8900560-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2014-12-02 | — | — | US | disclosed |
| US-20140235724-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2014-08-21 | — | — | US | disclosed |
| US-8425887-B2 | Amide dendrimer compositions | GENZYME CORPORATION (US) | 2013-04-23 | — | — | US | disclosed |
| US-20110142952-A1 | Pharmaceutical Compositions | HARRIS DAVID J | 2011-06-16 | — | — | US | disclosed |
| US-20100069500-A1 | AMIDE DENDRIMER COMPOSITIONS | GENZYME CORPORATION (US) | 2010-03-18 | — | — | US | disclosed |
| WO-2009154747-A1 | PHARMACEUTICAL COMPOSITIONS | GENZYME CORPORATION (US) | 2009-12-23 | — | — | WO | disclosed |
| EP-2066293-A2 | AMIDE DENDRIMER COMPOSITIONS | Genzyme Corporation (US) | 2009-06-10 | — | — | EP | disclosed |
| US-5350873-A | Optically active phenoxypropionic esters | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-27 | — | — | US | disclosed |
| EP-0583605-A1 | Defined oligomeric liquid crystalline compounds with smectic liquid crystalline phases | BASF Aktiengesellschaft (DE) | 1994-02-23 | — | — | EP | disclosed |
| EP-0528268-A2 | Optically active esters of phenoxypropionic acid | BASF Aktiengesellschaft (DE) | 1993-02-24 | — | — | EP | disclosed |
| EP-0504660-A2 | Liquid crystal compounds | BASF Aktiengesellschaft (DE) | 1992-09-23 | — | — | EP | disclosed |
| EP-0137900-B1 | BIS-PLATINUM COMPLEXES AS ANTITUMOR AGENTS | Andrulis Research Corporation (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4720504-A | Use of bis-platinum complexes as antitumor agents | ANDRULIS RESEARCH CORPORATION (US) | 1988-01-19 | — | — | US | disclosed |
| US-4565884-A | WATER SOLUBLE | ANDRULIS RESEARCH CORPORATION (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0137900-A1 | Bis-platinum complexes as antitumor agents | Andrulis Research Corporation (US) | 1985-04-24 | — | — | EP | disclosed |
| WO-1984004524-A1 | BIS-PLATINUM COMPLEXES AS ANTITUMOR AGENTS | ANDRULIS RES CORP (US) | 1984-11-22 | — | — | WO | disclosed |
| US-4015057-A | WITH AN ALIPHATIC CARBOXYLIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142952-A1 | Pharmaceutical Compositions | SRM, PARG, PARN | POLB 1952/4885TDP1 1355/4885CTDSP1 2546/4885 |
| US-20140235724-A1 | AMIDE DENDRIMER COMPOSITIONS | FABP2, PHOSPHO1, PAM | POLB 2395/4885TDP1 3877/4885CTDSP1 821/4885 |
| US-20100069500-A1 | AMIDE DENDRIMER COMPOSITIONS | FABP2, PHOSPHO1, PAM | POLB 2395/4885TDP1 3877/4885CTDSP1 821/4885 |
| US-20150321996-A1 | AMIDE DENDRIMER COMPOSITIONS | FABP2, PHOSPHO1, PAM | POLB 2395/4885TDP1 3877/4885CTDSP1 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.