SCHEMBL676573

SCHEMBL676573

O=C(O)C1C(C(=O)O)C1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
TSHR P16473 3/20 0.44
LMNA P02545 3/20 0.44
PMP22 Q01453 2/20 0.44
KDM4E B2RXH2 2/20 0.44
APEX1 P27695 1/20 0.44
GMNN O75496 1/20 0.44
TFPI2 P48307 1/20 0.44
TP53 P04637 1/20 0.44
NFKB1 P19838 1/20 0.44
THPO P40225 1/20 0.44
GRM2 Q14416 3/20 0.42
CYP2D6 P10635 3/20 0.42
CYP1A2 P05177 3/20 0.42
CYP2C19 P33261 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL66048 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL1963633 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL9782982 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL338159 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL9271352 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL9782992 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL9782989 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL9782996 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL9782987 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA
SCHEMBL911207 1.00 POLB (0.47) POLBTDP1CTDSP1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118947817-A Application of xylo-oligosaccharide in regulating rumen flora and metabolites of ruminants 宁夏大学 2024-11-15 CN claimed
CN-116355244-A Photo-cured cellulose-reinforced degradable polyester elastomer and preparation method thereof 浙江大学台州研究院 2023-06-30 CN claimed
CN-116355245-A Photo-cured bacterial cellulose reinforced degradable polyester elastomer and preparation method thereof 浙江大学台州研究院 2023-06-30 CN claimed
CN-113341043-B Method for deducing early death and post-death inundation time of corpse in water based on metabonomics marker and application thereof 中国医科大学 2022-11-25 CN claimed
EP-3377487-B1 COMPOUNDS FOR MEDICINAL APPLICATIONS AusVir Therapeutics Pty Ltd (AU) 2022-01-12 EP claimed
CN-113341043-A Method for deducing early death and post-death inundation time of corpse in water based on metabonomics marker and application thereof 中国医科大学 2021-09-03 CN claimed
US-11007274-B2 Compounds for medicinal applications AusVir Therapeutics Pty Ltd (AU) 2021-05-18 US claimed
EP-3377487-A1 COMPOUNDS FOR MEDICINAL APPLICATIONS Australian Biomedical Co. Pty Ltd (AU) 2018-09-26 EP claimed
US-20180264128-A1 COMPOUNDS FOR MEDICINAL APPLICATIONS Australian Biomedical Co. Pty Ltd. (AU) 2018-09-20 US claimed
US-8323678-B2 Implantable medical devices comprising poly[l-lactide-co-(3,6-dialkyl-1,4-dioxane-2,5-dione)] ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-12-04 US claimed
US-20110270387-A1 Implantable Medical Devices Comprising Poly[L-Lactide-Co-(3,6-Dialkyl-1,4-Dioxane-2,5-Dione)] ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2011-11-03 US claimed
EP-1792894-B1 Contrast agents GE HEALTHCARE AS (NO) 2010-09-22 EP claimed
US-7485753-B2 Contrast agents GE HEALTHCARE AS (NO) 2009-02-03 US claimed
US-20080199402-A1 Contrast Agents GE HEALTHCARE AS (NO) 2008-08-21 US claimed
EP-1792894-A2 Contrast agents GE Healthcare AS (NO) 2007-06-06 EP claimed
US-20070007489-A1 Heat transfer medium composition SHISHIAI-KABUSHIKIGAISHA (JP) 2007-01-11 US claimed
EP-1698678-A1 HEAT CARRIER COMPOSITION Shishiai-Kabushikigaisha (JP) 2006-09-06 EP claimed
JP-8311027-A None JP disclosed
US-4132702-A Phenol esters and amides and polymers stabilized therewith CIBA-GEIGY CORPORATION (US) 1979-01-02 US disclosed
US-3969294-A Segmented copolyester adhesives stabilized by alkaline earth oxides and carboxylic compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11007274-B2 Compounds for medicinal applications HAVCR2, ENGASE, DNPEP POLB 2756/4885TDP1 2545/4885CTDSP1 41/4885
US-20080199402-A1 Contrast Agents PYM1, MIA3, IPO11 POLB 3523/4885TDP1 2302/4885CTDSP1 2878/4885
US-20180264128-A1 COMPOUNDS FOR MEDICINAL APPLICATIONS HAVCR2, ENGASE, DNPEP POLB 2756/4885TDP1 2545/4885CTDSP1 41/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.