Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.47 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.47 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.47 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.47 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 3/20 | 0.48 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28084888 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL27221209 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL4361600 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6295851 | 0.98 | KMT2A (0.48) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5616273 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL25330776 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL22027281 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL22026910 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL22026959 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL28501552 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107400911-B | A method of Pd-Fe-Co-B composite membrane is prepared using plating-displacement | 安庆师范大学 | 2019-10-25 | — | — | CN | claimed |
| CN-107447208-A | A kind of method for preparing Pd Ni Fe P alloy films using chemical plating displacement | 安庆师范大学 | 2017-12-08 | — | — | CN | claimed |
| CN-107400911-A | A kind of method for preparing Pd Fe Co B composite membranes using plating displacement | 安庆师范大学 | 2017-11-28 | — | — | CN | claimed |
| CN-103898559-B | One utilizes ionic liquid electrodialysis to remove the method for As, Sb in copper electrolyte | ANQING NORMAL UNIVERSITY (CN) | 2016-04-06 | — | — | CN | claimed |
| CN-103898559-A | Method for removing As and Sb out of copper electrolyte by utilizing ionic liquid electrodialysis | UNIV ANQING NORMAL | 2014-07-02 | — | — | CN | claimed |
| US-12559586-B2 | Compositions containing uretdione groups crosslinking at low temperatures | COVESTRO DEUTSCHLAND AG (DE) | 2026-02-24 | — | — | US | disclosed |
| US-12239948-B2 | Materials based on natural pollen grains and uses thereof | MARQUETTE UNIVERSITY (US) | 2025-03-04 | — | — | US | disclosed |
| CN-117567412-A | Synthesis method of trimellitic anhydride dihydric phenol ester or dihydric alcohol ester | 江苏正丹化学工业股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20230192941-A1 | COMPOSITIONS CONTAINING URETDIONE GROUPS CROSSLINKING AT LOW TEMPERATURES | COVESTRO DEUTSCHLAND AG (DE) | 2023-06-22 | — | — | US | disclosed |
| US-20220250026-A1 | Materials Based on Natural Pollen Grains and Uses Thereof | MARQUETTE UNIVERSITY | 2022-08-11 | — | — | US | disclosed |
| WO-2020257316-A1 | MATERIALS BASED ON NATURAL POLLEN GRAINS AND USES THEREOF | MARQUETTE UNIVERSITY (US) | 2020-12-24 | — | — | WO | disclosed |
| CN-111925262-A | Preparation method of multi-component low-eutectic liquid based on metal chloride | 中国工程物理研究院化工材料研究所 | 2020-11-13 | — | — | CN | disclosed |
| WO-2009102419-A2 | ALUMINUM RECOVERY PROCESS | THE UNIVERSITY OF ALABAMA (US) | 2009-08-20 | — | — | WO | disclosed |
| CN-101473069-A | Method for preparing porous metal organic framework material | BASF AG (DE) | 2009-07-01 | — | — | CN | disclosed |
| CN-101218377-A | Method for producing porous metal-organic framework materials | BASF AG (DE) | 2008-07-09 | — | — | CN | disclosed |
| CN-1886536-A | Method for electrochemical production of a crystalline porous metal organic skeleton material | BASF AG (DE) | 2006-12-27 | — | — | CN | disclosed |
| CN-1070162-C | Catalytic composition and a process of olefins | INST FRANCAIS DU PETROLE (FR) | 2001-08-29 | — | — | CN | disclosed |
| US-5675051-A | Catalytic composition and olefin disproportion process | INSTITUT FRANCAIS DU PETROLE (FR) | 1997-10-07 | — | — | US | disclosed |
| US-5525567-A | Catalytic composition and olefin disproportion process | INSTITUT FRANCAIS DU PETROLE (FR) | 1996-06-11 | — | — | US | disclosed |
| CN-1106023-A | Catalytic composition and a process of olefins | INST FRANCAIS DU PETROLE (FR) | 1995-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559586-B2 | Compositions containing uretdione groups crosslinking at low temperatures | URB2, UQCRB, UQCRC2 | CHRM2 843/4885CHRM1 697/4885ACHE 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.