Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 19/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL4344184 | 0.99 | FBP1 (0.70) | FBP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL958688 | 0.98 | FBP1 (0.71) | FBP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL956186 | 0.81 | FBP1 (1.00) | FBP1 | |
| SCHEMBL4344180 | 0.80 | FBP1 (0.46) | FBP1ALDH1A1 | |
| SCHEMBL4344178 | 0.78 | FBP1 (0.44) | FBP1 | |
| SCHEMBL957498 | 0.77 | FBP1 (0.76) | FBP1 | |
| SCHEMBL958320 | 0.72 | FBP1 (0.64) | FBP1 | |
| SCHEMBL956677 | 0.70 | FBP1 (1.00) | FBP1 | |
| SCHEMBL19630984 | 0.70 | FBP1 (0.68) | FBP1 | |
| SCHEMBL9487941 | 0.69 | FBP1 (0.79) | FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032548-A1 | THIAZOLE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007137962-A1 | THIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-12-06 | — | — | WO | disclosed |