Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 8/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347850 | 0.82 | PLA2G10 (0.48) | PLA2G10BRD4PTK2MEN1ALDH1A1 | |
| SCHEMBL2195802 | 0.81 | PTK2 (0.39) | BRD4PTK2MEN1ALDH1A1MAPT | |
| SCHEMBL2197980 | 0.80 | PLA2G10 (0.44) | PLA2G10BRD4MEN1ALDH1A1KMT2A | |
| SCHEMBL2198463 | 0.78 | BRD4 (0.52) | BRD4MAPK1MAPK8CDC7BTK | |
| SCHEMBL2196825 | 0.76 | IKBKB (0.38) | PTK2MEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL2196669 | 0.75 | CDC7 (0.46) | MEN1ALDH1A1MAPTKMT2AMAPK8 | |
| SCHEMBL2198095 | 0.74 | CDC7 (0.57) | BRD4PTK2CDC7BTK | |
| SCHEMBL2199299 | 0.74 | IKBKB (0.42) | BRD4MEN1KMT2ACDC7 | |
| SCHEMBL2196674 | 0.74 | CDC7 (0.37) | BRD4MEN1KMT2AMAPK8CDC7 | |
| SCHEMBL220935 | 0.74 | CDC7 (0.51) | BRD4PTK2MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116530-B1 | NOVEL PYRROLE DERIVATIVE HAVING UREIDE GROUP AND AMINOCARBONYL GROUP AS SUBSTITUENTS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-14 | — | — | EP | disclosed |
| EP-2116530-A1 | NOVEL PYRROLE DERIVATIVE HAVING UREIDE GROUP AND AMINOCARBONYL GROUP AS SUBSTITUENTS | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-11 | — | — | EP | disclosed |