SCHEMBL2198463

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2195873	0.84	BRD4 (0.47)	BRD4JAK2IKBKBCDC7CDK1
	SCHEMBL4347544	0.83	BRD4 (0.47)	BRD4JAK2IKBKBCDC7CDK2
	SCHEMBL2196845	0.83	CDC7 (0.51)	BRD4JAK2IKBKBCDC7FFAR1
	SCHEMBL2196975	0.83	IKBKB (0.47)	BRD4JAK2IKBKBFFAR1
	SCHEMBL2198478	0.82	BRD4 (0.46)	BRD4CDC7
	SCHEMBL2196927	0.82	CDC7 (0.54)	BRD4IKBKBCDC7CDK1MAPK8
	SCHEMBL4343078	0.81	BRD4 (0.60)	BRD4JAK2KDM5AKDM4CKDM5B
	SCHEMBL2198565	0.80	BRD4 (0.50)	BRD4CDC7MAPK1MAPK8
	SCHEMBL2199465	0.80	BRD4 (0.43)	BRD4JAK2IKBKBCDC7CDK2
	SCHEMBL2200693	0.80	PARP1 (0.47)	BRD4JAK2CDC7FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.