SCHEMBL2197980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4351884	0.81	PLA2G10 (0.47)	PLA2G10CCNE2CCNE1CDK2BRD4
	SCHEMBL4344664	0.80	PLA2G10 (0.45)	PLA2G10BRD4ALDH1A1MEN1KMT2A
	SCHEMBL2199299	0.78	IKBKB (0.42)	CCNE2CCNE1CDK2BRD4IKBKB
	SCHEMBL2198463	0.76	BRD4 (0.52)	CDK2BRD4IKBKBJAK2JAK3
	SCHEMBL12509581	0.73	BRD4 (0.38)	BRD4JAK2CHEK1MEN1KMT2A
	SCHEMBL2196863	0.72	CDC7 (0.38)	CDK2BRD4ALDH1A1IKBKBJAK2
	SCHEMBL2198095	0.72	CDC7 (0.57)	BRD4CHEK1CDC7
	SCHEMBL2196674	0.72	CDC7 (0.37)	BRD4IKBKBJAK2JAK3CHEK1
	SCHEMBL2195873	0.71	BRD4 (0.47)	BRD4ALDH1A1IKBKBJAK2JAK3
	SCHEMBL4347544	0.71	BRD4 (0.47)	CCNE2CCNE1CDK2BRD4IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.