Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064127 | 0.80 | CHRNB4 (0.36) | RIPK1ALDH1A1SLC6A1 | |
| SCHEMBL12613814 | 0.79 | SLC6A11 (0.47) | SLC6A12MEN1KMT2APTGIRSLC6A1 | |
| SCHEMBL8727530 | 0.76 | MEN1 (0.43) | MEN1KMT2AKDM4E | |
| SCHEMBL8343315 | 0.76 | CHRNB4 (0.33) | SLC6A12BACE1ALDH1A1BCHEACHE | |
| SCHEMBL6855484 | 0.75 | SLC6A2 (0.32) | CHRM2 | |
| SCHEMBL8343429 | 0.75 | CHRNB4 (0.41) | CHRM2CHRM1CHRM3BACE1KDM4E | |
| SCHEMBL1260570 | 0.74 | SMN1; SMN2 (0.40) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL6849987 | 0.74 | SMN1; SMN2 (0.40) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| Lithium SCHEMBL29904177 | 0.74 | SMN1; SMN2 (0.41) | KDM4EALDH1A1MAPTNFE2L2 | |
| SCHEMBL28799825 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1MAPTNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021351-A2 | METHOD FOR THE SYNTHESIS OF TRIAZOLE-CONTAINING OLIGONUCLEOTIDE DERIVATIVES | Centre National de la Recherche Scientifique (FR) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007125429-A2 | METHOD FOR THE SYNTHESIS OF TRIAZOLE- CONTAINING OLIGONUCLEOTIDE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-11-08 | — | — | WO | disclosed |