Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.45 |
| ▸ | CES1 | P23141 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157814 | 0.86 | CES2 (0.47) | CES2CES1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL524133 | 0.86 | CES2 (0.47) | CES2CES1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6973235 | 0.85 | CYP1A2 (0.47) | CES2CES1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3864054 | 0.83 | CES2 (0.45) | CES2CES1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL597783 | 0.81 | EP300 (0.50) | CES2CES1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL597781 | 0.81 | EP300 (0.50) | CES2CES1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4622616 | 0.80 | EP300 (0.53) | CES2CES1NAAATBXAS1EP300 | |
| SCHEMBL5467265 | 0.80 | EP300 (0.53) | CES2CES1NAAATBXAS1EP300 | |
| SCHEMBL6258126 | 0.80 | EP300 (0.53) | CES2CES1NAAATBXAS1EP300 | |
| SCHEMBL6666634 | 0.80 | EP300 (0.53) | CES2CES1NAAATBXAS1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611752-B2 | Method of making a microstructured coated article | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-11-03 | — | — | US | disclosed |
| US-20080187678-A1 | MICROSTRUCTURED SUBSTRATES WITH PROFILE-PRESERVING ORGANOMETALLIC COATINGS | 3M INNOVATIVE PROPERTIES COMPANY | 2008-08-07 | — | — | US | disclosed |
| US-7288309-B2 | Microstructured substrates with profile-preserving organometallic coatings | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-10-30 | — | — | US | disclosed |
| US-20050089673-A1 | Microstructured substrates with profile-preserving organometallic coatings | 3M INNOVATIVE PROPERTIES COMPANY | 2005-04-28 | — | — | US | disclosed |
| US-6815043-B2 | FORMED VIA MONOMER VAPOR DEPOSITION | 3M INNOVATIVE PROPERTIES COMPANY | 2004-11-09 | — | — | US | disclosed |
| US-20030068436-A1 | Method of coating microstructured substrates with polymeric layer(s), allowing preservation of surface feature profile | 3M INNOVATIVE PROPERTIES COMPANY | 2003-04-10 | — | — | US | disclosed |
| EP-1159087-B1 | METHOD OF COATING MICROSTRUCTURED SUBSTRATES WITH POLYMERIC LAYER(S), ALLOWING PRESERVATION OF SURFACE FEATURE PROFILE | 3M INNOVATIVE PROPERTIES CO (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6503564-B1 | Method of coating microstructured substrates with polymeric layer(s), allowing preservation of surface feature profile | 3M INNOVATIVE PROPERTIES COMPANY | 2003-01-07 | — | — | US | disclosed |
| EP-1159087-A1 | METHOD OF COATING MICROSTRUCTURED SUBSTRATES WITH POLYMERIC LAYER(S), ALLOWING PRESERVATION OF SURFACE FEATURE PROFILE | 3M Innovative Properties Company (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000050179-A1 | METHOD OF COATING MICROSTRUCTURED SUBSTRATES WITH POLYMERIC LAYER(S), ALLOWING PRESERVATION OF SURFACE FEATURE PROFILE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |