Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 3/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 1.00 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA6 | P23280 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL418399 | 1.00 | CA5A (1.00) | CA5ACA5BCA2TSHRCA1 | |
| Sulfuric Acid SCHEMBL3699224 | 1.00 | CA5A (1.00) | CA5ACA5BCA2TSHRCA1 | |
| Sulfuric Acid SCHEMBL8532128 | 1.00 | CA5A (1.00) | CA5ACA5BCA2TSHRCA1 | |
| Sulfuric Acid SCHEMBL113 | 1.00 | — | — | |
| Sulfuric Acid SCHEMBL2555505 | 1.00 | CA5A (1.00) | CA5ACA5BCA2TSHRCA1 | |
| Sulfuric Acid SCHEMBL110268 | 1.00 | CA5A (1.00) | CA5ACA5BCA2TSHRCA1 | |
| Sulfuric Acid SCHEMBL562154 | 1.00 | CA5A (1.00) | CA5ACA5BCA2TSHRCA1 | |
| Sulfuric Acid SCHEMBL23440695 | 0.93 | CA5A (0.86) | CA5ACA5BCA2TSHRCA1 | |
| Sulfuric Acid SCHEMBL21813307 | 0.93 | CA5A (0.86) | CA5ACA5BCA2TSHRCA1 | |
| Sulfuric Acid SCHEMBL22639007 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896053-B1 | PHARMACEUTICAL COMPOSITION COMPRISING FGF18 AND IL-1 ANTAGONIST AND METHOD OF USE | ZYMOGENETICS INC (US) | 2018-10-31 | — | — | EP | claimed |
| EP-2419478-B1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI COR INC (US) | 2018-02-28 | — | — | EP | claimed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | claimed |
| CN-105837861-A | Composite natural polymer gel material | 苏鑫 | 2016-08-10 | — | — | CN | claimed |
| EP-1551426-B1 | METHODS OF ADMINISTERING FGF18 | ZYMOGENETICS INC (US) | 2014-06-25 | — | — | EP | claimed |
| EP-2630196-A1 | CYANINE DYES AND THEIR CONJUGATES | LI-COR, INC. (US) | 2013-08-28 | — | — | EP | claimed |
| US-8481752-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2013-07-09 | — | — | US | claimed |
| US-20130052637-A1 | OPTICAL FLUORESCENT IMAGING IN HISTOLOGY | LI-COR, INC. (US) | 2013-02-28 | — | — | US | claimed |
| WO-2012054749-A1 | CYANINE DYES AND THEIR CONJUGATES | LI-COR, INC. (US) | 2012-04-26 | — | — | WO | claimed |
| WO-2012054784-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2012-04-26 | — | — | WO | claimed |
| EP-0447351-B1 | Medicament for retaining ophthalmological agents in ocular tissues and method for its production | CHILDRENS MEDICAL CENTER (US) | 1996-01-10 | — | — | EP | claimed |
| EP-0423240-B1 | MODULATION OF VIRUS-HOST CELL INTERACTIONS USING CYCLIC OLIGOSACCHARIDES | UNIV PENNSYLVANIA (US) | 1995-11-08 | — | — | EP | claimed |
| US-5446030-A | With an anionic oligosaccharide | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE, A NON-PROFIT CORP. OF PA | 1995-08-29 | — | — | US | claimed |
| WO-1994022455-A1 | METHODS OF AFFECTING THE GROWTH OF LIVING TISSUE IN MAMMALS AND COMPOUNDS AND COMPOSITIONS THEREFOR | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-10-13 | — | — | WO | claimed |
| EP-0325199-B1 | Fumagillin as angiostatic agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-10-27 | — | — | EP | claimed |
| EP-0398925-B1 | GROWTH INHIBITING AGENT AND THE USE THEREOF | CHILDRENS HOSPITAL CORP (US) | 1993-10-20 | — | — | EP | claimed |
| US-5227372-A | METHOD FOR RETAINING OPHTHALMOLOGICAL AGENTS IN OCULAR TISSUES | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1993-07-13 | — | — | US | claimed |
| US-5135919-A | Using fumagillin | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1992-08-04 | — | — | US | claimed |
| EP-0447351-A1 | Medicament for retaining ophthalmological agents in ocular tissues and method for its production | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1991-09-18 | — | — | EP | claimed |
| CN-1038765-A | The F G F composition of stabilisation and production thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-01-17 | — | — | CN | claimed |