Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.80 |
| ▸ | HTR2C | P28335 | 11/20 | 0.80 |
| ▸ | HTR2B | P41595 | 11/20 | 0.80 |
| ▸ | HTR7 | P34969 | 6/20 | 0.80 |
| ▸ | HTR3A | P46098 | 3/20 | 0.80 |
| ▸ | HTR5A | P47898 | 2/20 | 0.80 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1E | P28566 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547149 | 0.89 | HTR7 (1.00) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL4356367 | 0.86 | HTR7 (0.79) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL1867192 | 0.84 | HTR7 (0.79) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL3441373 | 0.83 | HTR7 (0.58) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL22438600 | 0.80 | HTR7 (0.57) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL20547145 | 0.74 | HTR7 (1.00) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL20547197 | 0.73 | HTR7 (1.00) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL20547357 | 0.72 | HTR7 (1.00) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL16221083 | 0.72 | CHRM3 (0.56) | HTR2AHTR2CHTR2BHTR7HTR3A | |
| SCHEMBL5644368 | 0.72 | HTR7 (0.80) | HTR2AHTR2CHTR2BHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268814-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20090275558-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275558-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS | BDKRB2, BDKRB1, TRPV1 | HTR2A 646/4885HTR2C 784/4885HTR2B 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.