Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 7/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341690 | 0.74 | ALDH1A1 (0.34) | GAAALDH1A1MAPTCNR1KMT2A | |
| SCHEMBL4347288 | 0.70 | GAA (0.47) | GAAALDH1A1TSHRMAPTALOX15 | |
| SCHEMBL4353448 | 0.62 | — | — | |
| SCHEMBL4347278 | 0.57 | HPGD (0.59) | GAAALDH1A1MAPTKMT2APOLB | |
| SCHEMBL31085247 | 0.57 | TSHR (0.46) | ALDH1A1TSHRALOX15CNR1KDM4E | |
| SCHEMBL4354062 | 0.56 | ALDH1A1 (0.37) | ALDH1A1POLB | |
| SCHEMBL4358649 | 0.56 | ALOX15 (0.56) | GAAALDH1A1ALOX15KMT2AKDM4E | |
| SCHEMBL11587479 | 0.56 | HPGD (0.64) | ALDH1A1TSHRALOX15CNR1KMT2A | |
| SCHEMBL25388266 | 0.54 | KDM4E (0.64) | GAAALDH1A1TSHRMAPTALOX15 | |
| SCHEMBL2246805 | 0.54 | KDM4E (0.46) | ALDH1A1KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | disclosed |