Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 14/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 14/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929190 | 0.98 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4347567 | 0.95 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4343780 | 0.95 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4989871 | 0.93 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL929719 | 0.91 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL24855609 | 0.88 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL11955684 | 0.88 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9642750 | 0.87 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL18648723 | 0.87 | HDAC3 (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL18415503 | 0.87 | SELP (0.51) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9476087-B2 | Methods and compounds for detecting beta-lactamase activity | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-10-25 | — | — | US | disclosed |
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | UNIV NANYANG TECH (SG) | 2014-10-30 | — | — | US | disclosed |
| US-8802387-B2 | Methods and compounds for detecting beta-lactamase activity | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-08-12 | — | — | US | disclosed |
| US-20090275065-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | NANYANG TECHNOLOGICAL UNIVERSITY | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | LPO, MPO, GUSB | HDAC3 2194/4885HDAC1 800/4885HDAC2 2973/4885 |
| US-20090275065-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | LPO, MPO, GUSB | HDAC3 2182/4885HDAC1 805/4885HDAC2 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.