Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350159 | 0.89 | TSHR (0.34) | GAAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL4345604 | 0.75 | GAA (0.50) | GAAPOLBALDH1A1TSHRKDM4E | |
| SCHEMBL4341694 | 0.71 | HPGD (0.42) | GAAALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL4349466 | 0.68 | TSHR (0.46) | GAAPOLBTSHRKMT2A | |
| SCHEMBL27719180 | 0.65 | L3MBTL1 (0.46) | POLBALDH1A1TSHRHSD17B10KDM4E | |
| SCHEMBL4353448 | 0.65 | — | — | |
| SCHEMBL7491132 | 0.64 | NPC1 (0.62) | GAAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL30606872 | 0.64 | NPC1 (0.62) | GAAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL30606873 | 0.64 | NPC1 (0.62) | GAAPOLBALDH1A1TSHRHSD17B10 | |
| SCHEMBL11493699 | 0.63 | KDM4E (0.50) | POLBALDH1A1TSHRHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |