Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.37 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Synthalin SCHEMBL336302 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL1923256 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL11882788 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL3072659 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL10728151 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| SCHEMBL3069140 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL7146690 | 0.97 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL21715464 | 0.97 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL19994028 | 0.97 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 | |
| Synthalin SCHEMBL27953128 | 0.97 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1CYP1A2KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010641-A2 | PHARMACEUTICAL COMPOSITION FOR INCREASING CELLULAR HYPOXIC TOLERANCE | UNIVERSITE DE NICE SOPHIA ANTIPOLIS (FR) | 2012-01-26 | — | — | WO | claimed |
| US-20210253511-A1 | COMPOUNDS AND USES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS ASSOCIATE WITH OR AGGREVATED BY IMPARED MITOPHAGY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2021-08-19 | — | — | US | disclosed |
| US-20210253511-A1 | COMPOUNDS AND USES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS ASSOCIATE WITH OR AGGREVATED BY IMPARED MITOPHAGY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2021-08-19 | — | — | US | disclosed |
| WO-2019175873-A1 | COMPOUNDS AND USES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS ASSOCIATE WITH OR AGGRAVATED BY IMPARED MITOPHAGY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2019-09-19 | — | — | WO | disclosed |
| WO-2019175873-A1 | COMPOUNDS AND USES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS ASSOCIATE WITH OR AGGRAVATED BY IMPARED MITOPHAGY | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2019-09-19 | — | — | WO | disclosed |
| US-7833331-B2 | Non-toxic corrosion-protection pigments based on cobalt | UNIVERSITY OF DAYTON (US) | 2010-11-16 | — | — | US | disclosed |
| US-7789917-B2 | Amphoteric stilbene composition | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2010-09-07 | — | — | US | disclosed |
| US-7789958-B2 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090163628-A1 | NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT | STURGILL JEFFREY ALLEN | 2009-06-25 | — | — | US | disclosed |
| US-7537663-B2 | Corrosion-inhibiting coating | UNIVERSITY OF DAYTON (US) | 2009-05-26 | — | — | US | disclosed |
| US-20040104377-A1 | Non-toxic corrosion-protection pigments based on rare earth elements | UNIVERSITY OF DAYTON | 2004-06-03 | — | — | US | disclosed |
| US-20040020568-A1 | Non-toxic corrosion-protection conversion coats based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-02-05 | — | — | US | disclosed |
| US-20040016363-A1 | CORROSION-INHIBITING COATING | VENTURE LENDING & LEASING, IV, INC. | 2004-01-29 | — | — | US | disclosed |
| WO-2004009869-A2 | CORROSION-INHIBITING COATING FOR METAL SURFACES | UNIVERSITY OF DAYTON (US) | 2004-01-29 | — | — | WO | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253511-A1 | COMPOUNDS AND USES FOR THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS ASSOCIATE WITH OR AGGREVATED BY IMPARED MITOPHAGY | PINK1, BECN1, MFN2 | SMN1; SMN2 219/4885MEN1 3658/4885CYP1A2 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.