Sugi Predict

Sugi Predict / Compounds / Synthalin

Synthalin

Synthalin

SCHEMBL336302

N=C(N)NCCCCCCCCCCNC(=N)N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.67
▸ MEN1 O00255 1/20 0.67
▸ CYP1A2 P05177 1/20 0.67
▸ KMT2A Q03164 1/20 0.67
▸ ALOX15 P16050 1/20 0.54
▸ HIF1A Q16665 2/20 0.40
▸ ALB P02768 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ SPHK1 Q9NYA1 3/20 0.37
▸ PAOX Q6QHF9 2/20 0.37
▸ PRSS1 P07477 4/20 0.37
▸ F2 P00734 2/20 0.37
▸ PRSS2 P07478 2/20 0.37
▸ PRSS3 P35030 2/20 0.37
▸ TMPRSS6 Q8IU80 2/20 0.37
▸ ST14 Q9Y5Y6 2/20 0.37
▸ ALDH1A2 O94788 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434733 1.00 SMN1; SMN2 (0.67) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
SCHEMBL1923256 1.00 SMN1; SMN2 (0.67) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
SCHEMBL11882788 1.00 SMN1; SMN2 (0.67) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
SCHEMBL3072659 1.00 SMN1; SMN2 (0.67) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
SCHEMBL10728151 1.00 SMN1; SMN2 (0.67) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
SCHEMBL3069140 1.00 SMN1; SMN2 (0.67) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
Hydrochloric Acid SCHEMBL7146690 0.97 SMN1; SMN2 (0.64) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
Hydrochloric Acid SCHEMBL21715464 0.97 SMN1; SMN2 (0.64) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
Hydrochloric Acid SCHEMBL19994028 0.97 SMN1; SMN2 (0.64) SMN1; SMN2MEN1CYP1A2KMT2AALOX15
Synthalin SCHEMBL27953128 0.97 SMN1; SMN2 (0.64) SMN1; SMN2MEN1CYP1A2KMT2AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117297981-A Antibacterial dental repair material 北京化工大学 2023-12-29 — — CN claimed
CN-116601305-A Method and system for detecting central nervous system diseases by using peripheral body fluid multi-standard biomarker 浙江大学医学院附属第一医院 2023-08-15 — — CN claimed
US-7553403-B2 Reversible electrochemical sensors for polyions AUBURN UNIVERSITY (US) 2009-06-30 — — US claimed
EP-1644726-A1 REVERSIBLE ELECTROCHEMICAL SENSORS FOR POLYIONS Auburn University (US) 2006-04-12 — — EP claimed
US-20050023153-A1 Reversible electrochemical sensors for polyions AUBURN UNIVERSITY 2005-02-03 — — US claimed
WO-2005008232-A1 REVERSIBLE ELECTROCHEMICAL SENSORS FOR POLYIONS AUBURN UNIVERSITY (US) 2005-01-27 — — WO claimed
US-12639513-B2 Computer processes and interfaces for analyzing and suggesting improvements for text readability WordRake Holdings, LLC (US) 2026-05-26 — — US disclosed
US-12624010-B2 Dihydrooxazole and thiourea derivatives modulating the NLRP3 inflammasome pathway AC IMMUNE SA (CH) 2026-05-12 — — US disclosed
EP-4168395-B1 DIHYDROOXAZOLE AND THIOUREA OR UREA DERIVATIVES MODULATING THE NLRP3 INFLAMMASOME PATHWAY AC IMMUNE SA (CH) 2026-03-25 — — EP disclosed
WO-2025133307-A1 HETEROCYCLIC MODULATORS OF THE NLRP3 INFLAMMASOME PATHWAY AC IMMUNE SA (CH) 2025-06-26 — — WO disclosed
EP-4562009-A1 NOVEL COMPOUNDS AC Immune SA (CH) 2025-06-04 — — EP disclosed
EP-4554945-A1 PYRROLOTRIAZINE AND IMIDAZOTRIAZINE DERIVATIVES AS MODULATORS OF THE NLRP3 INFLAMMASOME PATHWAY AC Immune SA (CH) 2025-05-21 — — EP disclosed
CN-119837855-A Compounds for the treatment of bacterial infections and for the enhancement of antibiotics 乔治亚州大学研究基金会 2025-04-18 — — CN disclosed
US-20050023153-A1 Reversible electrochemical sensors for polyions AUBURN UNIVERSITY 2005-02-03 — — US disclosed
WO-2005008232-A1 REVERSIBLE ELECTROCHEMICAL SENSORS FOR POLYIONS AUBURN UNIVERSITY (US) 2005-01-27 — — WO disclosed
US-20040097562-A1 Method for treating tension-type headache HEAD EXPLORER APS (DK) 2004-05-20 — — US disclosed
US-20040097562-A1 Method for treating tension-type headache HEAD EXPLORER APS (DK) 2004-05-20 — — US disclosed
WO-2003068167-A2 NOVEL TREATMENT FOR PATHOLOGIES ASSOCIATED WITH OXIDATIVE DAMAGE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-08-21 — — WO disclosed
US-3931316-A Method of preparing O-methyl-isourea hydrogen sulfate and O-methyl-isourea sulfate from cyanamide SUDDEUTSCHE KALKSTICKSTOFF-WERKE AG (DT) 1976-01-06 — — US disclosed
US-3890446-A Certain diguanidino compounds used as fungicides MURPHY CHEMICAL LTD (GB) 1975-06-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624010-B2 Dihydrooxazole and thiourea derivatives modulating the NLRP3 inflammasome pathway NOD1, NLRP3, NLRP1 SMN1; SMN2 3878/4885MEN1 4498/4885CYP1A2 550/4885
US-12639513-B2 Computer processes and interfaces for analyzing and suggesting improvements for text readability SET, UPF1, NUDT21 SMN1; SMN2 1141/4885MEN1 658/4885CYP1A2 4543/4885
US-20040097562-A1 Method for treating tension-type headache GRIN3A, GRIN2A, GRIK4 SMN1; SMN2 4339/4885MEN1 859/4885CYP1A2 2737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.