Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559423 | 0.84 | HTR1A (0.70) | HTR1A | |
| Hydrochloric Acid SCHEMBL4343506 | 0.83 | HTR1A (0.69) | HTR1A | |
| Hydrochloric Acid SCHEMBL4559862 | 0.82 | HTR1A (0.68) | HTR1A | |
| Hydrochloric Acid SCHEMBL4337711 | 0.82 | HTR1A (0.68) | HTR1A | |
| SCHEMBL4347675 | 0.78 | HTR1A (0.70) | HTR1A | |
| SCHEMBL4350020 | 0.75 | HTR1A (0.68) | HTR1A | |
| SCHEMBL3556889 | 0.71 | HTR1A (0.74) | HTR1A | |
| SCHEMBL3557468 | 0.71 | HTR1A (0.79) | HTR1A | |
| SCHEMBL28770623 | 0.69 | HTR1A (0.85) | HTR1A | |
| SCHEMBL3557770 | 0.69 | HTR1A (1.00) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029577-A2 | CRYSTALLINE FORMS OF 6-METHOXY-8-[4-(1-(5-FLUORO)-QUINOLIN-8-YL-PIPERIDIN-4-YL)-PIPERAZIN-1-YL]-QUINOLINE | Wyeth (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007146116-A2 | CRYSTALLINE FORMS OF 6-METHOXY-8-[4-(1-(5-FLUORO)-QUINOLIN-8-YL-PIPERIDIN-4-YL)-PIPERAZIN-1-YL]-QUINOLINE | WYETH (US) | 2007-12-21 | — | — | WO | disclosed |