Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347700 | 1.00 | ANPEP (0.40) | ANPEPERAP2ERAP1DPP4CYP3A4 | |
| SCHEMBL1527219 | 0.87 | EPHX1 (0.48) | ANPEPALDH1A1MEN1KMT2AHTT | |
| SCHEMBL14860145 | 0.87 | EPHX1 (0.48) | ANPEPALDH1A1MEN1KMT2AHTT | |
| SCHEMBL14860143 | 0.87 | EPHX1 (0.48) | ANPEPALDH1A1MEN1KMT2AHTT | |
| SCHEMBL4346637 | 0.84 | DPP4 (0.44) | ANPEPERAP2ERAP1DPP4CYP3A4 | |
| SCHEMBL4346640 | 0.84 | DPP4 (0.44) | ANPEPERAP2ERAP1DPP4CYP3A4 | |
| SCHEMBL4343817 | 0.83 | RIPK1 (0.40) | ANPEPDPP4ENPEP | |
| SCHEMBL4359730 | 0.83 | SLC6A4 (0.50) | ANPEPDPP4CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL4343822 | 0.83 | RIPK1 (0.40) | ANPEPDPP4ENPEP | |
| SCHEMBL4359724 | 0.83 | SLC6A4 (0.50) | ANPEPDPP4CYP3A4ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |