Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359724 | 1.00 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3CYP3A4CYP1A2 | |
| SCHEMBL14860143 | 0.87 | EPHX1 (0.48) | LMNAANPEPALDH1A1HTTRAB9A | |
| SCHEMBL14860145 | 0.87 | EPHX1 (0.48) | LMNAANPEPALDH1A1HTTRAB9A | |
| SCHEMBL1527219 | 0.87 | EPHX1 (0.48) | LMNAANPEPALDH1A1HTTRAB9A | |
| SCHEMBL4343817 | 0.86 | RIPK1 (0.40) | DPP4DPP7ANPEPENPEP | |
| SCHEMBL4343822 | 0.86 | RIPK1 (0.40) | DPP4DPP7ANPEPENPEP | |
| SCHEMBL4344087 | 0.85 | PNMT (0.48) | SLC6A4SLC6A2SLC6A3DPP4DPP7 | |
| SCHEMBL4344081 | 0.85 | PNMT (0.48) | SLC6A4SLC6A2SLC6A3DPP4DPP7 | |
| SCHEMBL4349347 | 0.84 | LDHA (0.53) | SLC6A4CYP1A2CYP2D6CYP2C19PPARG | |
| SCHEMBL4349354 | 0.84 | LDHA (0.53) | SLC6A4CYP1A2CYP2D6CYP2C19PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |