Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11495907 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15414575 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1004629 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15104745 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9152986 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10389401 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5359205 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1259818 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1784250 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29420379 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9443 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026103385-A1 | INTEGRATED PREPARATION METHOD FOR IRON-BASED PHOSPHATE MATERIAL FOR POSITIVE ELECTRODE OF SECONDARY BATTERY | 深圳珈钠能源科技有限公司 | 2026-05-21 | — | — | WO | claimed |
| CN-122070327-A | Rubber composition and rubber product | 住友电气工业株式会社 | 2026-05-19 | — | — | CN | claimed |
| CN-122031300-A | Plant cellulose abrasive, preparation method and application thereof, and toothpaste and dentifrice prepared from plant cellulose abrasive | 广州纳英化工有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122032562-A | Metal-based catalyst and preparation method and application thereof | 东北大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122036505-A | CO production based on carbonate pyrolysis2Method for preparing dimethyl carbonate | 衢州资源化工创新研究院 | 2026-05-15 | — | — | CN | claimed |
| EP-4680586-B1 | OPTIMIZATION OF COLOR IN THE MECHANOCHEMICAL ACTIVATION OF CLAYS | thyssenkrupp Polysius GmbH (DE) | 2026-05-13 | — | — | EP | claimed |
| CN-122025437-A | Porous carbon material, manufacturing method thereof and application of porous carbon material in super capacitor | 中国石油化工股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122025438-A | Capacitor carbon and preparation method and application thereof | 中国石油化工股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122010081-A | Phosphate positive electrode material and carbon coating method thereof | 德阳川发龙蟒新材料有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12600695-B2 | Method for reactivating a precious metal iron catalyst and performing a chemical reaction | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-04-14 | — | — | US | claimed |
| US-4061716-A | Process for the production of sorbent solids for use in the desulfurization of gases | MCGAULEY PATRICK JOHN | 1977-12-06 | — | — | US | claimed |
| US-4036662-A | CALCINING | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | claimed |
| US-4036655-A | METAL BORATES AND WATER SOLUBLE SILICATES, COATINGS, ADHERENT LAYERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-07-19 | — | — | US | claimed |
| US-3992348-A | Method for the preparation of moldable filled polymetal acrylate | TRW SYSTEMS AND ENERGY (US) | 1976-11-16 | — | — | US | claimed |
| US-3968259-A | ENZYME | M & M LIVESTOCK PRODUCTS CO., INC. (US) | 1976-07-06 | — | — | US | claimed |
| US-3957894-A | CYCLIZATION, IRON COMPOUNDS, ORGANOALUMINUM COMPOUNDS, NITRIC OXIDE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JA) | 1976-05-18 | — | — | US | claimed |
| US-3951894-A | CHLORINE OR BROMINE ORGANIC FIRERETARDANT, ACRYLONITRILE-BUTADIENE-STYRENE POLYMER | UNIROYAL INC. (US) | 1976-04-20 | — | — | US | claimed |
| US-3950546-A | ALUMINUM SILICATE, SODIUM BENTONITE | MUSIC CITY SUPPLEMENT COMPANY (US) | 1976-04-13 | — | — | US | claimed |
| US-3950263-A | GAS COOLING AND FILTERING AGENT FOR AIR BAG GAS GENERATOR | NISSAN MOTOR CO., LTD. (JA) | 1976-04-13 | — | — | US | claimed |
| US-3936445-A | FROM ISOXAZOLE, AN O-PHENYLENEDIAMINE AND AN IRON COMPOUND | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | claimed |