Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9146197 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8059663 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL711064 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3261 | 0.94 | — | — | |
| Bicarbonate SCHEMBL9145494 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL532723 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL43479 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3266233 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1331961 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1537736 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7111847-B2 | Self-dispensing bullet trap buffer block | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2006-09-26 | — | — | US | claimed |
| US-20050006849-A1 | Self-dispensing bullet trap buffer block | US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2005-01-13 | — | — | US | claimed |
| EP-1412284-A2 | COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND | Runkis, Walter H. (US) | 2004-04-28 | — | — | EP | claimed |
| US-20030073580-A1 | Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof | RUNKIS WALTER H (US) | 2003-04-17 | — | — | US | claimed |
| WO-2002100772-A2 | COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS | RUNKIS WALTER H (US) | 2002-12-19 | — | — | WO | claimed |
| WO-2023249969-A1 | METHOD AND APPARATUS FOR ELECTRO-CHEMICAL TREATMENT OF CONTAMINATED WATER | Mainfraim Industries LLC (US) | 2023-12-28 | — | — | WO | disclosed |
| US-20230406731-A1 | METHOD AND APPARATUS FOR ELECTRO-CHEMICAL TREATMENT OF CONTAMINATED WATER | Mainfraim Industries LLC (US) | 2023-12-21 | — | — | US | disclosed |
| CN-107262029-A | A kind of high flame retardant carbon-supported catalyst and preparation method thereof | 昆明理工大学 | 2017-10-20 | — | — | CN | disclosed |
| US-7243921-B2 | Method providing self-dispensing additive from buffer blocks for use with a medium in a bullet trap | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2007-07-17 | — | — | US | disclosed |
| US-20070126184-A1 | Method providing self-dispensing additive from buffer blocks for use with a medium in a bullet trap | LARSON STEVEN L | 2007-06-07 | — | — | US | disclosed |
| US-7111847-B2 | Self-dispensing bullet trap buffer block | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2006-09-26 | — | — | US | disclosed |
| US-20050006849-A1 | Self-dispensing bullet trap buffer block | US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2005-01-13 | — | — | US | disclosed |
| EP-1412284-A2 | COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND | Runkis, Walter H. (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030073580-A1 | Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof | RUNKIS WALTER H (US) | 2003-04-17 | — | — | US | disclosed |
| WO-2002100772-A2 | COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS | RUNKIS WALTER H (US) | 2002-12-19 | — | — | WO | disclosed |