Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997350 | 0.78 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL997348 | 0.78 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL4346635 | 0.76 | P2RX3 (0.63) | P2RX3 | |
| SCHEMBL997980 | 0.76 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL997507 | 0.75 | P2RX3 (0.60) | P2RX3 | |
| SCHEMBL1046238 | 0.75 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL12951995 | 0.74 | P2RX3 (0.90) | P2RX3 | |
| SCHEMBL997285 | 0.74 | P2RX3 (0.59) | P2RX3 | |
| SCHEMBL12973619 | 0.73 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL4355291 | 0.73 | SOS1 (0.34) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136639-A1 | PYRID-2-YL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008123963-A1 | PYRID-2-YL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |