Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 3/20 | 0.32 |
| ▸ | HRH2 | P25021 | 3/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10425945 | 0.98 | ACHE (0.51) | ACHEPRMT6CNR2L3MBTL1BCHE | |
| Hydrochloric Acid SCHEMBL30087038 | 0.98 | ACHE (0.51) | ACHEPRMT6CNR2L3MBTL1BCHE | |
| Bromide SCHEMBL10425509 | 0.98 | ACHE (0.51) | ACHEPRMT6CNR2L3MBTL1BCHE | |
| Bromide SCHEMBL10425819 | 0.90 | ACHE (0.49) | ACHEPRMT6CNR2BCHEHRH2 | |
| SCHEMBL10425769 | 0.87 | ACHE (0.42) | ACHEPRMT6L3MBTL1HRH2SLC22A2 | |
| SCHEMBL11191077 | 0.87 | ACHE (0.41) | ACHEPRMT6CNR2CYP2D6HTR1A | |
| SCHEMBL10785243 | 0.85 | ACHE (0.40) | ACHEPRMT6L3MBTL1HRH2SLC22A2 | |
| Hydrochloric Acid SCHEMBL28891089 | 0.84 | ACHE (0.43) | ACHEPRMT6 | |
| SCHEMBL11069411 | 0.83 | ACHE (0.39) | ACHEPRMT6HTR1AHTR2AHTR7 | |
| SCHEMBL8341614 | 0.80 | ACHE (0.36) | ACHEL3MBTL1HRH2SLC22A2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117598316-A | New nicotine pesticide in fruits and vegetables and detection method of metabolite thereof | 舟山市食品药品检验检测研究院 | 2024-02-27 | — | — | CN | claimed |
| CN-1397553-A | Process for preparing Nizatidine | BIAN LUSHENG (CN) | 2003-02-19 | — | — | CN | claimed |
| EP-0116452-B1 | IMPROVEMENTS IN OR RELATING TO THE SYNTHESIS OF NIZATIDINE | ELI LILLY AND COMPANY (US) | 1993-01-13 | — | — | EP | claimed |
| US-4904792-A | N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1990-02-27 | — | — | US | claimed |
| EP-0230127-A1 | Synthesis of nizatidine | ELI LILLY AND COMPANY (US) | 1987-07-29 | — | — | EP | claimed |
| US-4587344-A | Isothiourea synthesis process | ELI LILLY AND COMPANY (US) | 1986-05-06 | — | — | US | claimed |
| EP-0116452-A2 | Improvements in or relating to the synthesis of nizatidine | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | claimed |
| CN-217809227-U | Nizatidine synthesis and refining equipment combination | 无棣融川医药化工科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-115108949-A | Method for preparing 2- (methylsulfonyl) ethylamine hydrochloride by using methyl mercaptan | 江苏恒沛药物科技有限公司 | 2022-09-27 | — | — | CN | disclosed |
| US-20090275622-A1 | NIZATIDINE FORMULATIONS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
| CN-1397553-A | Process for preparing Nizatidine | BIAN LUSHENG (CN) | 2003-02-19 | — | — | CN | disclosed |
| EP-0704214-B1 | Process for obtaining pure nizatidine | LILLY CO ELI (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0960880-A1 | Process for preparing intermediates to nizatidine and related compounds | ELI LILLY AND COMPANY (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0083186-A2 | Thiazole derivatives as H2-receptor antagonists | ELI LILLY AND COMPANY (US) | 1983-07-06 | — | — | EP | disclosed |
| US-4382090-A | N-Thiazolylmethylthioalkyl-N'alkylamidines and related compounds | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-4380639-A | ANTIULCER AND ANTISECRETORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4380638-A | ANTIULCER AND ANTISECRETORY AGENTS; DERIVATIVES OF 3-AMINO-4-HET-A | BRISTOL-MYERS COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4375547-A | ANTIHISTAMINES, 'I RECEPTOR ANTAGONISTS, ANTISECRETORY AGENTS | ELI LILLY AND COMPANY (US) | 1983-03-01 | — | — | US | disclosed |
| US-4374248-A | ANTIHISTAMINES, ANTIULCER | BRISTOL-MYERS COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
| EP-0049618-A1 | Improvements in or relating to 2,4-disubstituted thiazole derivatives | ELI LILLY AND COMPANY (US) | 1982-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275622-A1 | NIZATIDINE FORMULATIONS | SLC30A5, SLC39A11, NNMT | ACHE 1618/4885PRMT6 152/4885CNR2 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.