Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348503 | 1.00 | CYP2C19 (0.49) | CYP2C19CTSCRAB9ATRPM8SLC1A3 | |
| SCHEMBL1527219 | 0.79 | EPHX1 (0.48) | RAB9ASLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL14860145 | 0.79 | EPHX1 (0.48) | RAB9ASLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL14860143 | 0.79 | EPHX1 (0.48) | RAB9ASLC1A3SLC1A2SLC1A1LMNA | |
| SCHEMBL7685603 | 0.78 | TRPM8 (0.58) | CYP2C19TRPM8RIPK1POLBTDP1 | |
| SCHEMBL1027537 | 0.76 | TRPM8 (0.49) | CYP2C19RAB9ATRPM8RIPK1POLB | |
| SCHEMBL4347700 | 0.75 | ANPEP (0.40) | CYP2C19RAB9ALMNADPP4 | |
| SCHEMBL4347705 | 0.75 | ANPEP (0.40) | CYP2C19RAB9ALMNADPP4 | |
| SCHEMBL2753684 | 0.75 | CYP2C19 (0.44) | CYP2C19CTSCRAB9ASLC1A3SLC1A2 | |
| SCHEMBL1025811 | 0.74 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |