Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123403 | 0.84 | MMP2 (0.39) | PPARAMMP2MMP8MMP12HPGD | |
| SCHEMBL7973696 | 0.84 | PPARA (0.34) | PPARAMMP2MMP8MMP12ALDH1A1 | |
| SCHEMBL10341827 | 0.81 | VHL (0.37) | PPARAHPGDMAPTHTTHDAC6 | |
| SCHEMBL595476 | 0.79 | PPARA (0.45) | PPARAMMP2MMP8MMP12ALDH1A1 | |
| SCHEMBL11661758 | 0.79 | PPARA (0.60) | PPARAMMP2MMP8MMP12ALDH1A1 | |
| SCHEMBL9990153 | 0.78 | PPARA (0.44) | PPARAMMP2MMP8MMP12ALDH1A1 | |
| SCHEMBL22317120 | 0.78 | VHL (0.49) | PPARAMMP2MMP8MMP12ALDH1A1 | |
| SCHEMBL15740345 | 0.77 | LMNA (0.46) | PPARAMMP2MMP8MMP12ALDH1A1 | |
| SCHEMBL10341846 | 0.76 | — | — | |
| SCHEMBL1586577 | 0.76 | MMP2 (0.67) | MMP2MMP8MMP12ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |