Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SOD1 | P00441 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967940 | 0.86 | TRIM24 (0.55) | KDM4ELMNATRIM24MAPTNR1H4 | |
| SCHEMBL19384428 | 0.85 | LMNA (0.61) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL9324039 | 0.85 | MAOB (0.51) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL19384259 | 0.85 | LMNA (0.61) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL19384288 | 0.85 | LMNA (0.61) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL19384624 | 0.84 | MAOB (0.50) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL20535109 | 0.84 | MAOB (0.50) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL20535111 | 0.84 | MAOB (0.50) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL29985682 | 0.84 | MAOB (0.50) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL19384211 | 0.84 | MAOB (0.50) | MAOBHSD17B10ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117049961-A | Yeast dehydrogenase inhibitor derivative and synthesis method thereof | 苏州君叶生物医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-3865474-A1 | MODULATORS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN AND METHODS OF USE | AbbVie Overseas S.à r.l. (LU) | 2021-08-18 | — | — | EP | disclosed |
| WO-2020239656-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF HEPATITIS B | GALAPAGOS NV (BE) | 2020-12-03 | — | — | WO | disclosed |
| EP-3681864-A1 | MODULATORS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN AND METHODS OF USE | AbbVie Overseas S.à r.l. (LU) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019053634-A1 | MODULATORS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN AND METHODS OF USE | AbbVie S.à.r.l. (LU) | 2019-03-21 | — | — | WO | disclosed |
| CN-109293597-A | A kind of preparation method of Febuxostat | 安徽省庆云医药股份有限公司 | 2019-02-01 | — | — | CN | disclosed |
| EP-2794586-B1 | NEW AZIRIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2016-04-20 | — | — | EP | disclosed |
| US-8530460-B2 | Azetidine derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-09-10 | — | — | US | disclosed |
| US-8530460-B2 | Azetidine derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-09-10 | — | — | US | disclosed |
| WO-2013092616-A1 | NEW AZIRIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
| WO-2010151797-A2 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | UNIVERSITY OF MASSACHUSETTS (US) | 2010-12-29 | — | — | WO | disclosed |
| EP-0975710-B2 | POLYMER ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2009-06-10 | — | — | EP | disclosed |
| CN-101243047-A | Phenoxyacetic acids as PPAR delta activators | NOVO NORDISK AS (DK) | 2008-08-13 | — | — | CN | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |
| EP-0975710-B1 | POLYMER ELECTROLUMINESCENT DEVICE | KONINKL PHILIPS ELECTRONICS NV (NL) | 2003-09-10 | — | — | EP | disclosed |
| EP-1310540-A1 | Polymer electroluminescent device | Koninklijke Philips Electronics N.V. (NL) | 2003-05-14 | — | — | EP | disclosed |
| US-20020001732-A1 | POLYMER ELECTROLUMINESCENT DEVICE | U.S. PHILIPS CORPORATION | 2002-01-03 | — | — | US | disclosed |
| EP-0975710-A1 | POLYMER ELECTROLUMINESCENT DEVICE | Koninklijke Philips Electronics N.V. (NL) | 2000-02-02 | — | — | EP | disclosed |
| WO-1999021936-A1 | POLYMER ELECTROLUMINESCENT DEVICE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 1999-05-06 | — | — | WO | disclosed |