SCHEMBL4349961

SCHEMBL4349961

CCCCCC=C[Si](C)(Cl)Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.43
TRPV1 Q8NER1 2/20 0.43
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
TERT O14746 3/20 0.38
MAPT P10636 2/20 0.38
BLM P54132 2/20 0.38
HSD17B10 Q99714 2/20 0.38
FABP4 P15090 2/20 0.38
PTPN1 P18031 2/20 0.38
PPARG P37231 2/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
GMNN O75496 1/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4349959 1.00 FAAH (0.43) FAAHTRPV1ALDH1A1TSHRTERT
SCHEMBL4352989 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT
SCHEMBL4354355 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT
SCHEMBL4357213 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT
SCHEMBL4354350 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT
SCHEMBL8034538 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT
SCHEMBL4352987 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT
SCHEMBL4357215 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT
SCHEMBL4354367 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT
SCHEMBL4355514 0.98 FAAH (0.46) FAAHTRPV1TSHRTERTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1989253-B1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO LTD (JP) 2013-10-02 EP disclosed
EP-2024439-B1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO LTD (JP) 2012-06-27 EP disclosed
US-20090298980-A1 Curable Silicone Resin Composition and Cured Body Thereof DOW CORNING TORAY CO., LTD. (JP) 2009-12-03 US disclosed
US-20090099321-A1 Curable Silicone Resin Composition and Cured Body Thereof DOW CORNING TORAY COMPANY, LTD. (JP) 2009-04-16 US disclosed
EP-2024439-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2009-02-18 EP disclosed
EP-1989253-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2008-11-12 EP disclosed
WO-2007132932-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO., LTD. (JP) 2007-11-22 WO disclosed
WO-2007099863-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO., LTD. (JP) 2007-09-07 WO disclosed
EP-1125939-B1 Process for reducing the amount of linear siloxane in a mixture of linear and cyclic siloxanes DOW CORNING TORAY SILICONE (JP) 2005-08-10 EP disclosed
WO-2004005404-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED PRODUCT DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2004-01-15 WO disclosed
US-6448360-B2 USING BASIC CATALYST DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-09-10 US disclosed
EP-1125939-A1 Process for the production of cyclic siloxane Dow Corning Toray Silicone Co., Ltd. (JP) 2001-08-22 EP disclosed
US-20010011120-A1 Process for the production of cyclic siloxane DOW TORAY CO., LTD. (JP) 2001-08-02 US disclosed