SCHEMBL4354355

SCHEMBL4354355

CCCCCCC=C[Si](C)(Cl)Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.46
TRPV1 Q8NER1 1/20 0.46
TSHR P16473 2/20 0.41
TERT O14746 3/20 0.41
CYP1A2 P05177 2/20 0.41
MAPT P10636 2/20 0.41
CYP2C19 P33261 2/20 0.41
BLM P54132 2/20 0.41
HSD17B10 Q99714 2/20 0.41
FABP4 P15090 2/20 0.41
PTPN1 P18031 2/20 0.41
PPARG P37231 2/20 0.41
KMT2A Q03164 2/20 0.41
PPARD Q03181 2/20 0.41
PPARA Q07869 2/20 0.41
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4355513 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL4357213 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL4352989 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL4352987 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL4357215 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL4354367 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL8034538 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL4355514 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL4354350 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL4354369 1.00 FAAH (0.46) FAAHTRPV1TSHRTERTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111825710-B Alkoxysilyl group-containing organosilane compound, method for producing same, composition containing same, and cured product 信越化学工业株式会社 2024-08-23 CN disclosed
US-11739184-B2 Polysiloxazane compound having alkoxysilyl group, process for producing same, and composition and cured product including same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-29 US disclosed
US-11708460-B2 Alkoxysilyl group-containing organic silazane compound, method for producing same, composition containing same and cured product SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-07-25 US disclosed
US-20230192731-A1 PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2023-06-22 US disclosed
EP-3798252-B1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME SHINETSU CHEMICAL CO (JP) 2022-06-29 EP disclosed
US-20210095079-A1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-04-01 US disclosed
EP-3798252-A1 POLYSILOXAZANE COMPOUND HAVING ALKOXYSILYL GROUP, PROCESS FOR PRODUCING SAME, AND COMPOSITION AND CURED PRODUCT INCLUDING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2021-03-31 EP disclosed
CN-111825710-A Organosilazane compounds containing alkoxysilyl groups, process for their preparation, compositions containing them and cured products 信越化学工业株式会社 2020-10-27 CN disclosed
US-20200332071-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-22 US disclosed
EP-3725822-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT Shin-Etsu Chemical Co., Ltd. (JP) 2020-10-21 EP disclosed
CN-101395212-A Curable silicone resin composition and cured body thereof DOW CORNING TORAY CO LTD (JP) 2009-03-25 CN disclosed
EP-2024439-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2009-02-18 EP disclosed
EP-1989253-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2008-11-12 EP disclosed
WO-2007132932-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO., LTD. (JP) 2007-11-22 WO disclosed
WO-2007099863-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO., LTD. (JP) 2007-09-07 WO disclosed
EP-1125939-B1 Process for reducing the amount of linear siloxane in a mixture of linear and cyclic siloxanes DOW CORNING TORAY SILICONE (JP) 2005-08-10 EP disclosed
WO-2004005404-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED PRODUCT DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2004-01-15 WO disclosed
US-6448360-B2 USING BASIC CATALYST DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-09-10 US disclosed
EP-1125939-A1 Process for the production of cyclic siloxane Dow Corning Toray Silicone Co., Ltd. (JP) 2001-08-22 EP disclosed
US-20010011120-A1 Process for the production of cyclic siloxane DOW TORAY CO., LTD. (JP) 2001-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708460-B2 Alkoxysilyl group-containing organic silazane compound, method for producing same, composition containing same and cured product OR10J3, ALKBH1, ALKBH2 FAAH 3131/4885TRPV1 462/4885TSHR 4579/4885
US-20200332071-A1 ALKOXYSILYL GROUP-CONTAINING ORGANIC SILAZANE COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION CONTAINING SAME AND CURED PRODUCT OR10J3, ALKBH1, ALKBH2 FAAH 3131/4885TRPV1 462/4885TSHR 4579/4885
US-20230192731-A1 PROCESS FOR THE STEPWISE SYNTHESIS OF SILAHYDROCARBONS CCR4, SALL4, CCR2 FAAH 4381/4885TRPV1 4700/4885TSHR 4142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.