SCHEMBL435015

SCHEMBL435015

CC(OC(=O)C(C)Br)OC(=O)C(C)Br

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9764287 0.87 SMN1; SMN2 (0.31) TSHR
SCHEMBL6834987 0.82 TSHR (0.44) TSHR
SCHEMBL10471153 0.82
SCHEMBL10977028 0.81
SCHEMBL1778572 0.80
SCHEMBL10975721 0.76 LMNA (0.41) FAAH
SCHEMBL19046663 0.76 ALDH1A1 (0.36) TSHR
SCHEMBL5434607 0.75 SMN1; SMN2 (0.32) TSHR
SCHEMBL952339 0.75 SMN1; SMN2 (0.32) TSHR
SCHEMBL13647266 0.75 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2596062-B1 SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS ROHM & HAAS (US) 2019-09-18 EP disclosed
US-10273314-B2 Set-LRP polymerization of acrylates in the presence of acids ROHM AND HAAS COMPANY (US) 2019-04-30 US disclosed
US-20130245216-A1 SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2013-09-19 US disclosed
EP-2596062-A1 SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS Rohm and Haas Company (US) 2013-05-29 EP disclosed
US-20120226000-A1 POLYVINYL CHLORIDE CONTAINING MULTIARMED STAR COPOLYMERS Tekni-Plex ,Inc. (US) 2012-09-06 US disclosed
WO-2012012705-A1 SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS ROHM AND HAAS COMPANY (US) 2012-01-26 WO disclosed
WO-2010065809-A1 POLYVINYL CHLORIDE CONTAINING MULTIARMED STAR COPOLYMERS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2010-06-10 WO disclosed