Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 15/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351897 | 0.88 | THRA (0.41) | FFAR4THRATHRBFFAR1PTGER1 | |
| SCHEMBL4364043 | 0.79 | THRA (0.66) | FFAR4THRATHRBFFAR1 | |
| SCHEMBL5718289 | 0.78 | FFAR1 (0.52) | FFAR4THRATHRBFFAR1PTGER1 | |
| SCHEMBL5718097 | 0.71 | FFAR1 (0.49) | FFAR4THRATHRBFFAR1PTGER1 | |
| SCHEMBL4356742 | 0.71 | THRA (0.63) | FFAR4THRATHRBFFAR1 | |
| SCHEMBL4352064 | 0.68 | THRA (0.66) | FFAR4THRATHRBFFAR1 | |
| SCHEMBL4360622 | 0.67 | THRA (0.68) | FFAR4THRATHRBFFAR1 | |
| SCHEMBL4346561 | 0.67 | THRB (0.64) | FFAR4THRATHRBFFAR1 | |
| SCHEMBL4531208 | 0.67 | THRA (0.64) | FFAR4THRATHRBFFAR1 | |
| SCHEMBL4559404 | 0.67 | THRA (0.64) | FFAR4THRATHRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | claimed |