Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 11/20 | 0.47 |
| ▸ | TAB1 | Q15750 | 11/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 4/20 | 0.39 |
| ▸ | FYN | P06241 | 4/20 | 0.39 |
| ▸ | AXL | P30530 | 4/20 | 0.39 |
| ▸ | FLT4 | P35916 | 4/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.39 |
| ▸ | FRK | P42685 | 4/20 | 0.39 |
| ▸ | CLK2 | P49760 | 4/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 4/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 4/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 4/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351213 | 1.00 | MAP3K7 (0.47) | MAP3K7TAB1PRKD3EGFRNTRK1 | |
| SCHEMBL13821437 | 0.88 | DHFR (0.41) | MAP3K7TAB1CDK1SYKDYRK1A | |
| SCHEMBL4343461 | 0.85 | PRKD3 (0.53) | MAP3K7TAB1PRKD3EGFRNTRK1 | |
| SCHEMBL4343457 | 0.85 | PRKD3 (0.53) | MAP3K7TAB1PRKD3EGFRNTRK1 | |
| SCHEMBL16932959 | 0.83 | GSK3B (0.56) | MAP3K7TAB1PRKD3EGFRNTRK1 | |
| SCHEMBL16932960 | 0.83 | GSK3B (0.56) | MAP3K7TAB1PRKD3EGFRNTRK1 | |
| SCHEMBL4346709 | 0.82 | MAP3K7 (0.48) | MAP3K7TAB1NTRK1ROCK1ROCK2 | |
| SCHEMBL4346713 | 0.82 | MAP3K7 (0.48) | MAP3K7TAB1NTRK1ROCK1ROCK2 | |
| SCHEMBL18238325 | 0.81 | MAP3K7 (0.47) | MAP3K7TAB1PRKD3EGFRNTRK1 | |
| SCHEMBL16945216 | 0.81 | MAP3K7 (0.47) | MAP3K7TAB1PRKD3EGFRNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | claimed |
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |