Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434855 | 0.93 | TRPA1 (0.38) | TRPV1OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL10084067 | 0.80 | TRPV1 (0.41) | TRPV1OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL15380860 | 0.80 | TRPV1 (0.41) | TRPV1OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL436051 | 0.78 | KDM4E (0.36) | TRPV1OPRK1CYP3A4CYP2D6 | |
| SCHEMBL10084062 | 0.77 | MEN1 (0.44) | TRPV1KCNH2MCHR2MCHR1CYP3A4 | |
| SCHEMBL434120 | 0.77 | KCNH2 (0.37) | TRPV1OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL434121 | 0.77 | KCNH2 (0.37) | TRPV1OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL432562 | 0.76 | NOS3 (0.40) | CYP3A4CYP2D6TRPA1 | |
| SCHEMBL15380879 | 0.74 | TRPV1 (0.39) | TRPV1OPRD1OPRM1OPRK1KCNH2 | |
| SCHEMBL434043 | 0.73 | HTT (0.42) | CYP3A4ENPP2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | claimed |