Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | BLVRB | P30043 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435001 | 0.81 | LRRK2 (0.39) | RAB9ANPC1MAPK1CCNE1CDK2 | |
| SCHEMBL2399248 | 0.80 | NOTUM (0.34) | RAB9ANPC1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL5188682 | 0.77 | ALDH1A1 (0.43) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6455148 | 0.71 | NISCH (0.59) | KMT2AMEN1NISCHKDM4EALDH1A1 | |
| SCHEMBL8473218 | 0.69 | HPGD (0.53) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3758939 | 0.68 | ALDH1A1 (0.37) | KMT2ASMN1; SMN2MEN1NISCHADORA1 | |
| SCHEMBL3759980 | 0.68 | PDE10A (0.36) | RAB9ANPC1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL3751748 | 0.68 | BACE1 (0.38) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3759693 | 0.68 | CYP2A6 (0.37) | RAB9ANPC1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL5066129 | 0.68 | MAPK1 (0.47) | RAB9ANPC1PKMKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |