SCHEMBL435162

SCHEMBL435162

Oc1c(Oc2ccccc2)cc(Cl)c(Cl)c1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.68
PNLIP P16233 1/20 0.43
TSHR P16473 2/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TTR P02766 2/20 0.42
DPP4 P27487 1/20 0.42
ACLY P53396 1/20 0.42
ALDH1A1 P00352 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PARG Q86W56 1/20 0.41
STK39 Q9UEW8 1/20 0.41
LTA4H P09960 2/20 0.41
NR1H2 P55055 1/20 0.41
BAX Q07812 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10437110 0.89 AKR1B1 (0.52) AKR1B1PNLIPTSHRHPGDHSD17B10
SCHEMBL29542318 0.85 AKR1B1 (0.47) AKR1B1PNLIPTSHRHPGDMAPK1
SCHEMBL3688370 0.82 CYP3A4 (0.47) AKR1B1PNLIPTSHRCYP1A2CYP3A4
SCHEMBL4575982 0.82 AKR1B1 (1.00) AKR1B1TSHRHPGDMAPK1HSD17B10
SCHEMBL30168074 0.82 AKR1B1 (1.00) AKR1B1TSHRHPGDMAPK1HSD17B10
SCHEMBL10425326 0.79 CYP1A2 (0.44) AKR1B1PNLIPTSHRHPGDCYP1A2
SCHEMBL4239846 0.79 ALDH1A1 (0.45) AKR1B1PNLIPTSHRCYP1A2CYP3A4
SCHEMBL10770746 0.78 TTR (0.46) AKR1B1PNLIPTSHRCYP1A2CYP3A4
SCHEMBL10937945 0.78 CYP1A2 (0.53) PNLIPTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL10936260 0.77 TTR (0.53) PNLIPHPGDCYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986777-A Polytetrafluoroethylene composition, high-efficiency antibacterial polytetrafluoroethylene porous membrane, and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-117603054-A Sterilizing reagent and application thereof 深圳市三启药物开发有限公司 2024-02-27 CN claimed
CN-116998496-A Wet tissue disinfectant, preparation method thereof and disinfectant wet tissue 杭州朗索医用消毒剂有限公司 2023-11-07 CN claimed
CN-116903948-A Antibacterial plastic and preparation method thereof 镇江宇烨新材料科技有限公司 2023-10-20 CN claimed
CN-116762808-A Concentrated acidic phenol disinfectant and preparation method thereof 山东利尔康医疗科技股份有限公司 2023-09-19 CN claimed
CN-116509827-A Clean skin disinfectant and application thereof 天津大学 2023-08-01 CN claimed
CN-116403463-A Liver model, human body model, operation navigation method, preparation method and system 上海市第十人民医院 2023-07-07 CN claimed
CN-112515989-B Compound low-alcohol disinfectant and preparation method thereof 上海利康消毒高科技有限公司 2023-06-02 CN claimed
CN-116115546-A Skin-moistening hand-washing-free gel disinfectant 山东博鹏生物技术有限公司 2023-05-16 CN claimed
CN-115300655-A Sell cabinet handle disinfection system 常熟市恒仕达电器有限公司 2022-11-08 CN claimed
US-5628989-A CONTAINING SPHERICAL SILICONE RUBBER POWDER WITH SPECIFIED PARTICLE SIZE AND HARDNESS; SPREAD WELL, SMOOTH, DRY FEEL DOW CORNING TORAY SILICONE CO., LTD. (JP) 1997-05-13 US claimed
WO-1996029983-A1 SKIN CARE PRODUCTS CONTAINING ANTI-ITCHING/ANTI-IRRITANT AGENTS COLGATE-PALMOLIVE COMPANY (US) 1996-10-03 WO claimed
US-5556577-A High foaming nonionic surfactant based liquid detergent COLGATE-PALMOLIVE CO. (US) 1996-09-17 US claimed
EP-0510151-B1 IMPROVED ANTI-PLAQUE COMPOSITIONS COMPRISING A COMBINATION OF MORPHOLINOAMINO ALCOHOL AND ANTI-MICROBIAL AGENT PHARMACIA AB (SE) 1995-04-05 EP claimed
EP-0510151-A1 IMPROVED ANTI-PLAQUE COMPOSITIONS COMPRISING A COMBINATION OF MORPHOLINOAMINO ALCOHOL AND ANTI-MICROBIAL AGENT. WARNER LAMBERT CO (US) 1992-10-28 EP claimed
WO-1992008442-A1 IMPROVED ANTI-PLAQUE COMPOSITIONS COMPRISING A COMBINATION OF MORPHOLINOAMINO ALCOHOL AND ANTI-MICROBIAL AGENT WARNER-LAMBERT COMPANY (US) 1992-05-29 WO claimed
EP-0176523-A4 CLEANING AGENT. SEATON KENNETH EDWIN 1986-07-29 EP claimed
EP-0176523-A1 CLEANING AGENT SEATON, Kenneth Edwin (AU) 1986-04-09 EP claimed
WO-1985004184-A1 CLEANING AGENT SEATON KENNETH EDWIN 1985-09-26 WO claimed
US-4118332-A USEFUL IN DETERGENTS COLGATE-PALMOLIVE COMPANY (US) 1978-10-03 US claimed