Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | F2R | P25116 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121252 | 0.85 | GAA (0.62) | GAASMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL11718411 | 0.84 | GAA (0.54) | GAASMN1; SMN2MAPTNPSR1HSD17B10 | |
| SCHEMBL11717437 | 0.84 | GAA (0.54) | GAASMN1; SMN2MAPTNPSR1HSD17B10 | |
| SCHEMBL4980566 | 0.83 | GAA (0.64) | GAASMN1; SMN2MAPTMTNR1BMAPK1 | |
| SCHEMBL29816965 | 0.83 | GAA (0.58) | GAASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL23142737 | 0.83 | GAA (0.58) | GAASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL14045181 | 0.82 | GAA (0.59) | GAASMN1; SMN2MAPTMTNR1BMAPK1 | |
| SCHEMBL9340695 | 0.81 | SMN1; SMN2 (0.67) | GAASMN1; SMN2MAPTNPSR1MTNR1B | |
| SCHEMBL6647977 | 0.80 | MTNR1B (0.82) | GAASMN1; SMN2MAPTNPSR1MTNR1B | |
| SCHEMBL7565149 | 0.80 | MAPK1 (0.81) | SMN1; SMN2MAPTMTNR1BMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576034-B2 | Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof | EKA CHEMICALS AB (SE) | 2009-08-18 | — | — | US | claimed |
| US-20040260081-A1 | Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof | EKA CHEMICALS AB (SE) | 2004-12-23 | — | — | US | claimed |
| EP-1427525-A2 | CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF | Chirosep (FR) | 2004-06-16 | — | — | EP | claimed |
| WO-2003026793-A2 | CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF | EKA CHEMICALS AB (SE) | 2003-04-03 | — | — | WO | claimed |
| US-7576034-B2 | Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof | EKA CHEMICALS AB (SE) | 2009-08-18 | — | — | US | disclosed |
| EP-1606320-B1 | CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF | CHIROSEP (FR) | 2007-06-13 | — | — | EP | disclosed |
| EP-1606320-A1 | CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF | CHIROSEP (FR) | 2005-12-21 | — | — | EP | disclosed |
| US-20040265267-A1 | Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof | CHIROSEP (FR) | 2004-12-30 | — | — | US | disclosed |
| US-20040260081-A1 | Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof | EKA CHEMICALS AB (SE) | 2004-12-23 | — | — | US | disclosed |
| WO-2004085485-A1 | CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF | CHIROSEP (FR) | 2004-10-07 | — | — | WO | disclosed |
| EP-1427525-A2 | CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF | Chirosep (FR) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003026793-A2 | CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF | EKA CHEMICALS AB (SE) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040265267-A1 | Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof | UROD, ALG1, NOTUM | GAA 4634/4885SMN1; SMN2 3848/4885MAPT 1394/4885 |
| US-20040260081-A1 | Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof | MTCL3, OR10J3, MCM4 | GAA 4638/4885SMN1; SMN2 4169/4885MAPT 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.