SCHEMBL7565149

SCHEMBL7565149

CCOC(=O)Nc1cccc(NC(=O)OCC)c1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.81
LMNA P02545 2/20 0.81
MAPT P10636 1/20 0.81
HSD17B10 Q99714 1/20 0.81
ALDH1A1 P00352 1/20 0.71
NPC1 O15118 4/20 0.68
HTT P42858 2/20 0.68
F2R P25116 1/20 0.68
SMN1; SMN2 Q16637 2/20 0.64
MTNR1B P49286 1/20 0.61
HPGD P15428 4/20 0.60
RAB9A P51151 4/20 0.60
CYP1A2 P05177 2/20 0.60
CYP2C9 P11712 2/20 0.60
CYP2C19 P33261 2/20 0.60
CRHBP P24387 1/20 0.58
CRHR2 Q13324 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2D6 P10635 1/20 0.58
KDM4E B2RXH2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565151 0.95 MAPK1 (0.79) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL3424143 0.91 MAPK1 (0.69) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL1933135 0.90 MAPK1 (0.68) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL13665249 0.89 RAB9A (0.78) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL9479621 0.89 MAPK1 (0.97) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL3117227 0.88 MAPK1 (0.66) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL1189665 0.88 MAPT (0.66) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL21349100 0.88 MAPK1 (0.66) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL1188378 0.88 MAPT (0.66) MAPK1LMNAMAPTHSD17B10ALDH1A1
SCHEMBL8591930 0.88 MAPK1 (0.66) MAPK1LMNAMAPTHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200225581-A1 PHOTOSENSITIVE RESIN COMPOSITION, OPTICAL FILM, AND METHOD OF PRODUCING OPTICAL FILM ECHEM SOLUTIONS CORP. (TW) 2020-07-16 US disclosed
EP-0855393-B1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KK (JP) 2002-08-14 EP disclosed
US-5922882-A ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1999-07-13 US disclosed
EP-0855393-A1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1998-07-29 EP disclosed
US-4487713-A HEAT TREATMENT WITH TITANIUM, TIN, ANTIMONY OR ZIRCONIUM COMPOUND EXXON RESEARCH & ENGINEERING CO. (US) 1984-12-11 US disclosed
EP-0061013-B1 PROCESS FOR THE PREPARATION OF POLYISOCYANATES BAYER AG (DE) 1984-06-27 EP disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0061013-A1 Process for the preparation of polyisocyanates BAYER AG (DE) 1982-09-29 EP disclosed
US-4081472-A CATALYTIC, FROM A CARBAMATE MITSUI TOATSU CHEMICALS INC. (JA) 1978-03-28 US disclosed