SCHEMBL43517

SCHEMBL43517

CC(Nc1ccc2ccccc2c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
GAA P10253 2/20 0.54
NPC1 O15118 7/20 0.53
MAPT P10636 3/20 0.53
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 1/20 0.52
HPGD P15428 1/20 0.52
HSD17B10 Q99714 1/20 0.52
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
CYP1A2 P05177 2/20 0.49
KDM4E B2RXH2 2/20 0.49
CYP2C19 P33261 1/20 0.49
HIF1A Q16665 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 4/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288854 1.00 RAB9A (0.54) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL29350028 1.00 RAB9A (0.54) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL29478375 1.00 RAB9A (0.54) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL43518 1.00 RAB9A (0.54) RAB9ASMN1; SMN2GAANPC1MAPT
Hydrochloric Acid SCHEMBL2351807 0.98 RAB9A (0.53) RAB9ASMN1; SMN2GAANPC1MAPT
Hydrochloric Acid SCHEMBL2351803 0.98 RAB9A (0.53) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL8624223 0.95 RAB9A (0.49) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL29928621 0.95 RAB9A (0.49) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL1021968 0.95 RAB9A (0.49) RAB9ASMN1; SMN2GAANPC1MAPT
Valine SCHEMBL9675573 0.90 SLC1A3 (0.47) RAB9ASMN1; SMN2GAANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7956 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
US-12540161-B2 Linkers BICYCLETX LIMITED (GB) 2026-02-03 US claimed
US-20250340595-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) BICYCLETX LTD (GB) 2025-11-06 US claimed
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
EP-3746467-B1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE SANOFI SA (FR) 2025-10-08 EP claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
EP-4613259-A1 PHARMACEUTICAL, DERMATOLOGICAL OR COSMETIC COMPOUNDS AND COMPOSITIONS FOR REDUCING MELANIN SYNTHESIS, STIMULATING TYPE I COLLAGEN PRODUCTION, SKIN DEPIGMENTATION AND/OR PROMOTING A SKIN ANTI-AGING EFFECT IN AN INDIVIDUAL OR ANIMAL, USES AND METHODS Chemyunion Ltda (BR) 2025-09-10 EP claimed
EP-4613260-A1 COMPOUNDS AND COSMETIC, DERMOCOSMETIC, COSMECEUTICAL OR PHARMACEUTICAL COMPOSITIONS FOR RELAXING MUSCLES, INCLUDING THE SKELETAL MUSCLES OF THE FACE, FOR ANTI-AGING COSMETIC ACTION, FOR REDUCING AND/OR SMOOTHING EXPRESSION LINES AND WRINKLES AND/OR FOR ANTIPERSPIRANT ACTION, USES AND METHODS Chemyunion Ltda (BR) 2025-09-10 EP claimed
US-20250277012-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. 2025-09-04 US claimed
EP-4582436-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BicycleTX Limited (GB) 2025-07-09 EP claimed
EP-0372537-A2 Urea derivatives of dipeptides with enzyme-inhibiting properties, process to make them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-13 EP claimed
EP-0370382-A2 Urea dipeptide derivatives with a renin-inhibiting activity, process to produce them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0370454-A2 Renin-inhibiting amino diol derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0370383-A2 Renin-inhibiting dipeptides, process to make them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP claimed
EP-0329013-A2 Renin-inhibiting amino acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-23 EP claimed
US-4855286-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
EP-0310015-A2 Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP claimed
EP-0255082-A2 Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-03 EP claimed
EP-0239874-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-07 EP claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed