SCHEMBL43518

SCHEMBL43518

C[C@H](Nc1ccc2ccccc2c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
GAA P10253 2/20 0.54
NPC1 O15118 7/20 0.53
MAPT P10636 3/20 0.53
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 1/20 0.52
HPGD P15428 1/20 0.52
HSD17B10 Q99714 1/20 0.52
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
CYP1A2 P05177 2/20 0.49
KDM4E B2RXH2 2/20 0.49
CYP2C19 P33261 1/20 0.49
HIF1A Q16665 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 4/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43517 1.00 RAB9A (0.54) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL288854 1.00 RAB9A (0.54) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL29350028 1.00 RAB9A (0.54) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL29478375 1.00 RAB9A (0.54) RAB9ASMN1; SMN2GAANPC1MAPT
Hydrochloric Acid SCHEMBL2351807 0.98 RAB9A (0.53) RAB9ASMN1; SMN2GAANPC1MAPT
Hydrochloric Acid SCHEMBL2351803 0.98 RAB9A (0.53) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL8624223 0.95 RAB9A (0.49) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL29928621 0.95 RAB9A (0.49) RAB9ASMN1; SMN2GAANPC1MAPT
SCHEMBL1021968 0.95 RAB9A (0.49) RAB9ASMN1; SMN2GAANPC1MAPT
Valine SCHEMBL9675573 0.90 SLC1A3 (0.47) RAB9ASMN1; SMN2GAANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10148 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
EP-4717776-A2 POLYPEPTIDE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS Ohio State Innovation Foundation (US) 2026-04-01 EP claimed
US-12589171-B2 177-Lu labeled peptide for site-specific uPAR-targeting TRT INNOVATIONS APS (DK) 2026-03-31 US claimed
EP-4709739-A1 ANTI-BACTERIAL PEPTIDES Agency for Science, Technology and Research (SG) 2026-03-18 EP claimed
EP-4448020-B1 UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR (UPAR)-PET/CT IN NEUROENDOCRINE NEOPLAMS CURASIGHT AS (DK) 2026-02-04 EP claimed
US-12540161-B2 Linkers BICYCLETX LIMITED (GB) 2026-02-03 US claimed
EP-4678194-A1 THERAPEUTIC APPLICATION OF 64CU-LABELLED CONJUGATES FOR SITE-SPECIFIC UPAR-TARGETING Curasight A/S (DK) 2026-01-14 EP claimed
US-12473265-B2 Methods for preparing PSMA conjugates ENDOCYTE, INC. (US) 2025-11-18 US claimed
US-20250340595-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) BICYCLETX LTD (GB) 2025-11-06 US claimed
EP-4644570-A1 HELICASE MUTANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN HIGH-THROUGHPUT SEQUENCING BGI Shenzhen (CN) 2025-11-05 EP claimed
US-4771124-A Parathyroid hormone antagonists with simplified synthetic methodology MERCK & CO., INC. (US) 1988-09-13 US claimed
EP-0255082-A2 Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-03 EP claimed
EP-0239874-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-07 EP claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed
EP-0145258-B1 NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH, USEFUL AS LHRH AGONISTS, AND PROCESSES FOR THEIR PREPARATION SYNTEX (U.S.A.) INC. (US) 1987-04-15 EP claimed
EP-0215171-A2 Peptides THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) 1987-03-25 EP claimed
EP-0214872-A2 Somatostatin analoge The Administrators of The Tulane Educational Fund (US) 1987-03-18 EP claimed
EP-0197798-A2 Peptides THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) 1986-10-15 EP claimed
EP-0171477-A2 Amino acid-containing therapeutic compounds THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) 1986-02-19 EP claimed
EP-0145258-A1 Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonists, and processes for their preparation SYNTEX (U.S.A.) INC. (US) 1985-06-19 EP claimed