SCHEMBL4351927

SCHEMBL4351927

CC(=O)N1C(C)(C)CC(NC(=O)C2CCCCC2)CC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 3/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CYP2D6 P10635 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
GAA P10253 1/20 0.42
CYP3A4 P08684 1/20 0.42
RAB9A P51151 1/20 0.42
EPHX2 P34913 4/20 0.41
ALDH1A1 P00352 5/20 0.40
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14008370 0.82 GAA (0.46) L3MBTL1TSHRMAPK1NPSR1CYP2D6
SCHEMBL4350938 0.78 HPGD (0.57) NPSR1GAAEPHX2LMNA
SCHEMBL30335962 0.76 GAA (0.55) L3MBTL1TSHRMAPK1NPSR1GAA
SCHEMBL4438119 0.75 GAA (0.48) L3MBTL1TSHRMAPK1NPSR1CYP2D6
Hydrochloric Acid SCHEMBL4959722 0.73 GAA (0.50) L3MBTL1TSHRMAPK1NPSR1CYP2D6
SCHEMBL9008680 0.72 KDM4E (0.33) L3MBTL1GAAEPHX2LMNA
SCHEMBL9300925 0.72 EPHX2 (0.37) GAAEPHX2
SCHEMBL14276927 0.72 EPHX2 (0.70) L3MBTL1TSHRMAPK1CYP2D6HRH3
Hydrochloric Acid SCHEMBL4432072 0.72 GAA (0.49) L3MBTL1TSHRMAPK1NPSR1CYP2D6
SCHEMBL2454323 0.72 HPGD (0.57) MAPK1NPSR1CYP3A4RAB9AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090251643-A1 POLARIZING PLATE, MANUFACTURING METHOD OF POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2009-10-08 US disclosed