SCHEMBL4351978

SCHEMBL4351978

ClCc1ccccc1-c1ncc[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1A1 P48729 1/20 0.49
TYRO3 Q06418 1/20 0.49
DYRK1B Q9Y463 1/20 0.49
NISCH Q9Y2I1 2/20 0.48
MTOR P42345 1/20 0.48
ADK P55263 1/20 0.48
ADRA1A P35348 1/20 0.43
IDO1 P14902 1/20 0.41
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.40
CASP6 P55212 1/20 0.39
MC4R P32245 2/20 0.38
ADRA2A P08913 2/20 0.38
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
TAAR1 Q96RJ0 2/20 0.37
KCNK13 Q9HB14 1/20 0.37
HTR1A P08908 1/20 0.36
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8541248 0.82 CSNK1A1 (0.49) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL9665277 0.82 CSNK1A1 (0.53) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL5855095 0.82 CSNK1A1 (0.53) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL17304239 0.82 CSNK1A1 (0.53) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL8537574 0.81 CSNK1A1 (0.47) CSNK1A1TYRO3DYRK1BNISCHMTOR
Hydrochloric Acid SCHEMBL27626087 0.81 CSNK1A1 (0.51) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL9287236 0.80 NISCH (0.64) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL29214244 0.79 CSNK1A1 (0.46) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL6951802 0.79 CSNK1A1 (0.50) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL6538599 0.79 TAAR1 (0.54) CSNK1A1TYRO3DYRK1BNISCHMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7614145-B2 Method for manufacturing multilayer circuit board and resin base material ZEON CORPORATION (JP) 2009-11-10 US disclosed
US-20050153059-A1 Partial plating method, partially-plated resin base, method for manufacturing multilayered circuit board ZEON CORPORATION (JP) 2005-07-14 US disclosed
US-20040237295-A1 Multilayer circuit board and resin base material, and its production method ZEON CORPORATION (JP) 2004-12-02 US disclosed
US-5753682-A Imidazole lipoxygenase inhibitors PFIZER INC. (US) 1998-05-19 US disclosed
EP-0703913-B1 IMIDAZOLES AS LIPOXYGENASE INHIBITORS PFIZER (US) 1997-06-11 EP disclosed
EP-0703913-A1 IMIDAZOLE LIPOXYGENASE INHIBITORS PFIZER (US) 1996-04-03 EP disclosed
WO-1994029299-A1 IMIDAZOLE LIPOXYGENASE INHIBITORS PFIZER INC. (US) 1994-12-22 WO disclosed