Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27626087 | 0.98 | CSNK1A1 (0.51) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL8541248 | 0.82 | CSNK1A1 (0.49) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL17304239 | 0.82 | CSNK1A1 (0.53) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL4351978 | 0.82 | CSNK1A1 (0.49) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL9665277 | 0.82 | CSNK1A1 (0.53) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL8537574 | 0.81 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL9287236 | 0.80 | NISCH (0.64) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL29214244 | 0.79 | CSNK1A1 (0.46) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL6951802 | 0.79 | CSNK1A1 (0.50) | CSNK1A1TYRO3DYRK1BNISCHMTOR | |
| SCHEMBL6538599 | 0.79 | TAAR1 (0.54) | CSNK1A1TYRO3DYRK1BNISCHMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699771-A | Cryptotanshinone compound, as well as preparation method and application thereof | 常州大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-101253144-B | Process for preparing aniline | SYNGENTA PARTICIPATIONS AG | 2011-11-23 | — | — | CN | disclosed |
| CN-100441585-C | Rhodium and iridium complexes | COVION ORGANIC SEMICONDUCTORS (DE) | 2008-12-10 | — | — | CN | disclosed |
| CN-101253144-A | Process for preparing aniline | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-27 | — | — | CN | disclosed |
| CN-100343263-C | Rhodium and iridium complexes | COVION ORGANIC SEMICONDUCTORS (DE) | 2007-10-17 | — | — | CN | disclosed |
| US-7144899-B2 | Thrombin inhibitors | MERCK & CO., INC. (US) | 2006-12-05 | — | — | US | disclosed |
| CN-1276960-C | Method of improving performance of refrigerant systems | COGNIS CORP (US) | 2006-09-27 | — | — | CN | disclosed |
| US-7026324-B2 | Thrombin inhibitors | MERCK & CO., INC. (US) | 2006-04-11 | — | — | US | disclosed |
| CN-1678617-A | Rhodium and iridium complexes | COVION ORGANIC SEMICONDUCTORS (DE) | 2005-10-05 | — | — | CN | disclosed |
| CN-1500093-A | Rhodium and iridium complexes | �����л��뵼������˾ | 2004-05-26 | — | — | CN | disclosed |
| US-20040097730-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2004-05-20 | — | — | US | disclosed |
| US-20040073025-A1 | Thrombin inhibitors | MERCK SHARP & DOHME CORP. | 2004-04-15 | — | — | US | disclosed |
| EP-1359913-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-6610701-B2 | For therapy and prophylaxis of blood coagulation and cardiovascular disorders | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |
| US-20020193398-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2002-12-19 | — | — | US | disclosed |
| WO-2002064211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| WO-2002064140-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| WO-2002064559-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| CN-1354776-A | Method for improving performance of refrigeration system | COGNIS CORP (US) | 2002-06-19 | — | — | CN | disclosed |
| EP-0194746-A2 | Pyridine derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097730-A1 | Thrombin inhibitors | F3, F2, SERPINC1 | CSNK1A1 2247/4885TYRO3 478/4885DYRK1B 4173/4885 |
| US-20020193398-A1 | Thrombin inhibitors | F2, F3, TFPI | CSNK1A1 3419/4885TYRO3 1469/4885DYRK1B 4309/4885 |
| US-20040073025-A1 | Thrombin inhibitors | F2, F11, F10 | CSNK1A1 1986/4885TYRO3 2426/4885DYRK1B 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.