Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613204 | 0.84 | CSNK1A1 (0.46) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL8538742 | 0.83 | CYP1A2 (0.48) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL15809922 | 0.82 | CYP1A2 (0.47) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL31419337 | 0.82 | CYP1A2 (0.47) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL8540682 | 0.82 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL24353016 | 0.82 | MAP3K8 (0.44) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL8537355 | 0.82 | CSNK1A1 (0.43) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL4351978 | 0.82 | CSNK1A1 (0.49) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL5855095 | 0.82 | CSNK1A1 (0.53) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 | |
| SCHEMBL8541248 | 0.82 | CSNK1A1 (0.49) | CSNK1A1TYRO3DYRK1BHTR1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11737349-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-08-22 | — | — | US | disclosed |
| US-20160368907-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-12-22 | — | — | US | disclosed |
| US-20150344433-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-03 | — | — | US | disclosed |
| CN-101228000-B | Water-soluble preflux and use thereof | SHIKOKU CHEM | 2010-06-09 | — | — | CN | disclosed |
| CN-101228000-A | Water-soluble preflux and use thereof | SHIKOKU CHEM (JP) | 2008-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344433-A1 | PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF | PRMT5, PRMT1, PRMT3 | CSNK1A1 406/4885TYRO3 3344/4885DYRK1B 1677/4885 |
| US-11737349-B2 | Organic electroluminescent materials and devices | OCIAD2, OCIAD1, OTC | CSNK1A1 4871/4885TYRO3 4705/4885DYRK1B 4553/4885 |
| US-20160368907-A1 | PRMT5 INHIBITORS AND USES THEREOF | PRMT5, PRMT1, PRMT6 | CSNK1A1 342/4885TYRO3 3289/4885DYRK1B 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.