Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354062 | 0.86 | ALDH1A1 (0.37) | ALDH1A1NPSR1ACACBPOLBHPGD | |
| SCHEMBL4358658 | 0.77 | GAA (0.34) | GAAALDH1A1NPSR1KMT2AALOX15 | |
| SCHEMBL4347288 | 0.76 | GAA (0.47) | GAAALDH1A1KMT2AALOX15MAPT | |
| SCHEMBL10521823 | 0.74 | TPMT (0.39) | ALDH1A1KMT2AALOX15MEN1TSHR | |
| SCHEMBL4345604 | 0.71 | GAA (0.50) | GAAALDH1A1KMT2AALOX15MAPT | |
| SCHEMBL4353434 | 0.69 | HPGD (0.61) | GAAALDH1A1KMT2ATSHRPOLB | |
| SCHEMBL4351639 | 0.69 | HPGD (0.59) | GAAALDH1A1MAPTTSHRHPGD | |
| SCHEMBL4348067 | 0.67 | GAA (0.43) | GAAALDH1A1KMT2AALOX15MEN1 | |
| SCHEMBL4346468 | 0.66 | GAA (0.41) | GAAALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4354055 | 0.65 | HPGD (0.41) | GAAALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | disclosed |